Protein Alignment mAChR-C and taar10a

DIOPT Version :10

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001076367.1
• Gene: taar10a / 794359
• ZFINID: ZDB-GENE-041014-55
• Length: 336
• Species: Danio rerio
• Alignment Length: 318
• Identity: 87/318 - (27%)
• Similarity: 142/318 - (44%)
• Gaps: 51/318 - (16%)

  Fly    51 LLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCV-GLALPYHLV----- 109
            ||::..:....:.|: ||:|.|:.|...|.|.:. :|..||||||:|..| |:.:|..::
Zfish    39 LLYMLFSISSIITII-GNLLVIITVVHFRQLHTP-TNYLILSLAVADLLVGGVVMPPSMLRSIET 101

  Fly   110 -FYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIF 173
             :|:|...      |.:...|.:..|..|:|.|..|::|||.|:.:...|...||......:||.
Zfish   102 CWYLGDLF------CKIHSSLDVTLCTASILNLCIISLDRYYAICHPFQYHSKMTSLATLIMIII 160

  Fly   174 NWCLGALVALLPVFWN-RWPDAQACEFDEVLAPG--YIAGVITPGFVIIWICMFL-------VYW 228
            .|.:.|::....:|.. .....:...::.:...|  ::....|.|.|...||.::       ||.
Zfish   161 CWTVSAVLGFGMIFMELNILGVEDFYYENIRCDGGCFVFQSKTGGTVFSLICFYIPAFVMLGVYL 225

  Fly   229 RIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYF-CVAIAQL 292
            :|:.||.:|...: |||           |..|..:.|:.:.:..|||.|...|:|:| |..|..|
Zfish   226 KILHEAQRQVQAI-QSV-----------NSELKKEGKATKTLAIIMGVFLTFWIPFFLCNLIDPL 278

  Fly   293 --FSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRAF--------VQTLCCRT 340
              :|:   .|:::.....:...||..|||:|::..|.||.||        .||...||
Zfish   279 IGYSV---PSLVFDLFLWVGYYNSTCNPIVYAFFYSWFRHAFRVILSKRVFQTNSSRT 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	76/291 (26%)
		TM helix 1	53..78	CDD:410626	6/24 (25%)
		TM helix 2	86..111	CDD:410626	11/31 (35%)
		TM helix 3	123..153	CDD:410626	11/29 (38%)
		TM helix 4	166..185	CDD:410626	4/18 (22%)
		TM helix 5	204..229	CDD:410626	8/33 (24%)
		TM helix 6	261..291	CDD:410626	10/30 (33%)
		TM helix 7	300..325	CDD:410626	7/24 (29%)
taar10a	NP_001076367.1	7tmA_TAAR1	38..317	CDD:320438	81/300 (27%)
		TM helix 1	39..65	CDD:320438	8/26 (31%)
		TM helix 2	72..98	CDD:320438	11/25 (44%)
		TM helix 3	110..140	CDD:320438	11/29 (38%)
		TM helix 4	152..175	CDD:320438	4/22 (18%)
		TM helix 5	201..230	CDD:320438	8/28 (29%)
		TM helix 6	246..276	CDD:320438	9/29 (31%)
		TM helix 7	285..310	CDD:320438	7/24 (29%)