Protein Alignment mAChR-C and si:dkey-247m21.3

DIOPT Version :10

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_017208337.2
• Gene: si:dkey-247m21.3 / 559089
• ZFINID: ZDB-GENE-091204-249
• Length: 390
• Species: Danio rerio
• Alignment Length: 360
• Identity: 94/360 - (26%)
• Similarity: 147/360 - (40%)
• Gaps: 48/360 - (13%)

  Fly    31 NATETPTEITLQATSFGAGHLLWLAINAFLFVLILG-GNILTIVAVRTCRHLRSVISNLFILSLA 94
            :|.::..|:..:.||     .:.|:|.....:::.. ||:|.:||:...|.||...:|.||:|||
Zfish     7 SAEDSVDEVVSKHTS-----RITLSIVLVTIIIMTALGNLLVMVALCKDRQLRKKKTNFFIVSLA 66

  Fly    95 VSDFCVGL-ALPYHLVFYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAV-VYALH 157
            .:|..|.| .:|...:.............||:|..|.:.....|:|.|..||:|||.|: ...|.
Zfish    67 FADLLVALVVMPLAAIELTTGKWNYGETFCLVRTSLDVLLTTASILHLCCIALDRYYAICCQPLV 131

  Fly   158 YRRYMTRRVAYSIIIFNWCLGALVALLPVF--WN-------------RWPDAQACEFDEVLAPGY 207
            |...||......:::..|.:...::.||:.  ||             .......|.|  ::...|
Zfish   132 YNNKMTPVRVSLMLVGCWVIPFFISFLPIMQSWNTIGIESFIEQRKLNSSRNSTCVF--MVNQPY 194

  Fly   208 IAGVITPGFVIIWICMFLVYWRIMREASKQALRLRQ---------SVVYNTDEATTMRNLLLHPD 263
            ........|.:..:.|.|.|.||...|...|.|:..         |...|.|:..:.|   :..:
Zfish   195 ALVCSAVAFYVPLVLMVLAYQRIYVTAMGHARRIGSLHRAGSAPTSTYPNNDQHGSSR---IKNE 256

  Fly   264 WKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGF 328
            .|:.:.:..|||||.|||.|:|...:...|........::.....|...||.|||.:|::.|..|
Zfish   257 TKAAKTLAVIMGCFCLCWAPFFVTNVVDPFINYSVPWQMWTAWLWLGYINSGLNPFLYAFLNRAF 321

  Fly   329 RRAFVQTLCC-----------RTARQCEDQLPADS 352
            ||||:..|||           ..:|||.:.:...|
Zfish   322 RRAFLMILCCGDERYARQGGFSPSRQCSESVNGTS 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	77/298 (26%)
		TM helix 1	53..78	CDD:410626	7/25 (28%)
		TM helix 2	86..111	CDD:410626	10/25 (40%)
		TM helix 3	123..153	CDD:410626	13/30 (43%)
		TM helix 4	166..185	CDD:410626	1/18 (6%)
		TM helix 5	204..229	CDD:410626	5/24 (21%)
		TM helix 6	261..291	CDD:410626	11/29 (38%)
		TM helix 7	300..325	CDD:410626	7/24 (29%)
si:dkey-247m21.3	XP_017208337.2	7tmA_5-HT4	23..325	CDD:320184	81/306 (26%)
		TM helix 1	24..50	CDD:320184	7/25 (28%)
		TM helix 2	58..84	CDD:320184	10/25 (40%)
		TM helix 3	96..126	CDD:320184	13/29 (45%)
		TM helix 4	139..162	CDD:320184	3/22 (14%)
		TM helix 5	191..220	CDD:320184	7/28 (25%)
		TM helix 6	254..284	CDD:320184	11/29 (38%)
		TM helix 7	293..318	CDD:320184	7/24 (29%)