Protein Alignment mAChR-C and Taar7f

DIOPT Version :10

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001010839.1
• Gene: Taar7f / 435207
• MGIID: 3527447
• Length: 358
• Species: Mus musculus
• Alignment Length: 311
• Identity: 80/311 - (25%)
• Similarity: 137/311 - (44%)
• Gaps: 28/311 - (9%)

  Fly    51 LLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALPYHLV----- 109
            |:..|:..|..||.:.||:|.:.::...|.|.|. :|..:.|||.:||.|| :.:|:.:|
Mouse    48 LILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSP-ANFLVASLACADFLVGVMVMPFSMVRSVEG 111

  Fly   110 -FYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIF 173
             :|.|...      |.|.....:..|..|:..|..|:|||||||...|.|....|..|:...|.|
Mouse   112 CWYFGDSY------CKLHTCFDVSFCYCSLFHLCFISVDRYIAVSDPLAYPTRFTASVSGKCITF 170

  Fly   174 NWCLGALVALLPVFWNRWPDAQACEFDEVLAPGYIAG---VITPGFVIIWICMFL--------VY 227
            :|.|........::...   ::|...|.|.:...:.|   .:...:|.|...:||        ||
Mouse   171 SWLLSISYGFSLIYTGA---SEAGLEDLVSSLTCVGGCQIAVNQTWVFINFSVFLIPTLVMITVY 232

  Fly   228 WRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQL 292
            .:|...|.:||..:.:........:.:.::.:...:.|:.:.:...:..|.|.|||||..:....
Mouse   233 SKIFLIAKQQAQNIEKMSKQTARASDSYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSFIDA 297

  Fly   293 FSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRAFVQTLCCRTARQ 343
            |....:.:.:|:....:...|||:||:||::....||:|...|:..:..|:
Mouse   298 FLGFITPTYVYEILVWIVYYNSAMNPLIYAFFYPWFRKAIKLTVTGKILRE 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	74/289 (26%)
		TM helix 1	53..78	CDD:410626	7/24 (29%)
		TM helix 2	86..111	CDD:410626	10/31 (32%)
		TM helix 3	123..153	CDD:410626	12/29 (41%)
		TM helix 4	166..185	CDD:410626	5/18 (28%)
		TM helix 5	204..229	CDD:410626	7/35 (20%)
		TM helix 6	261..291	CDD:410626	8/29 (28%)
		TM helix 7	300..325	CDD:410626	8/24 (33%)
Taar7f	NP_001010839.1	7tm_GPCRs	49..337	CDD:475119	76/297 (26%)
		TM helix 1	50..74	CDD:410628	7/23 (30%)
		TM helix 2	83..105	CDD:410628	9/21 (43%)
		TM helix 3	121..143	CDD:410628	5/21 (24%)
		TM helix 4	166..182	CDD:410628	4/15 (27%)
		TM helix 5	210..233	CDD:410628	5/22 (23%)
		TM helix 6	272..294	CDD:410628	7/21 (33%)
		TM helix 7	305..330	CDD:410628	8/24 (33%)