Protein Alignment mAChR-C and Taar7d

DIOPT Version :10

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001010838.1
• Gene: Taar7d / 435206
• MGIID: 3527443
• Length: 358
• Species: Mus musculus
• Alignment Length: 346
• Identity: 87/346 - (25%)
• Similarity: 150/346 - (43%)
• Gaps: 44/346 - (12%)

  Fly    19 ALGVVPFLWQHQNA------TETPTEITLQ-------ATSFGAG-HLLWLAINAFLFVLILGGNI 69
            |.|...|.|...:.      :.|.||:..:       .:.:..| .|:..|:..|..||.:.||:
Mouse     2 ATGDDSFPWDQDSILSRDLFSATSTELCYENLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNL 66

  Fly    70 LTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALPYHLV------FYMGSDIGAMRGPCLLRF 127
            |.:.::...|.|.|. :|..:.|||.:||.|| :.:|:.:|      :|.|........ |....
Mouse    67 LVMTSILHFRQLHSP-ANFLVASLACADFLVGVMVMPFSMVRSVEGCWYFGESYCKFHS-CFEGS 129

  Fly   128 FLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVFWNRWP 192
            |     |..|:..|..|:|||||||...|.|....|..|:...|.|:|    |::::..|...:.
Mouse   130 F-----CYSSLFHLCFISVDRYIAVSDPLTYPTRFTASVSGKCITFSW----LLSIIYSFSLLYT 185

  Fly   193 DAQACEFDEVLAPGYIAG----VITPGFVIIWICMFL--------VYWRIMREASKQALRLRQSV 245
            .|.....:::::.....|    .:...:|.|...:||        ||.:|...|.:||..:.:..
Mouse   186 GANDAGLEDLVSALTCVGGCQIAVNQTWVFINFLLFLIPTLVMITVYSKIFLIAKQQAQNIEKMS 250

  Fly   246 VYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLA 310
            ......:.:.::.:...:.|:.:.:...:..|.|.|||||..:|...|....:.:.:|:....:.
Mouse   251 KQTARASESYKDRVTKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFITPTYVYEILVWIV 315

  Fly   311 IANSALNPIIYSWKNSGFRRA 331
            ..|||:||:||::..|.||:|
Mouse   316 YYNSAMNPLIYAFFYSWFRKA 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	74/290 (26%)
		TM helix 1	53..78	CDD:410626	7/24 (29%)
		TM helix 2	86..111	CDD:410626	10/31 (32%)
		TM helix 3	123..153	CDD:410626	12/29 (41%)
		TM helix 4	166..185	CDD:410626	5/18 (28%)
		TM helix 5	204..229	CDD:410626	7/36 (19%)
		TM helix 6	261..291	CDD:410626	9/29 (31%)
		TM helix 7	300..325	CDD:410626	8/24 (33%)
Taar7d	NP_001010838.1	7tm_GPCRs	49..337	CDD:475119	78/299 (26%)
		TM helix 1	50..74	CDD:410628	7/23 (30%)
		TM helix 2	83..105	CDD:410628	9/21 (43%)
		TM helix 3	121..143	CDD:410628	6/27 (22%)
		TM helix 4	166..182	CDD:410628	5/19 (26%)
		TM helix 5	210..233	CDD:410628	5/22 (23%)
		TM helix 6	272..294	CDD:410628	7/21 (33%)
		TM helix 7	305..330	CDD:410628	8/24 (33%)