Protein Alignment mAChR-C and CG13579

DIOPT Version :10

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 76/422 - (18%)
• Similarity: 137/422 - (32%)
• Gaps: 168/422 - (39%)

  Fly    56 INAFLFVL----ILGGNILTIVAVRTCRHLRSVIS--NLFILSLAVSDFCVGLAL---------- 104
            |.|.|.::    ::|.|.|.|..:...|:...:..  ...:.|||::|..:||.:
  Fly    39 IEAVLILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLTSLALNDLTIGLLITPFGLMPALF 103

  Fly   105 ---PYHLVFYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRV 166
               ||..:|            |.::..|.......|.:.|:.:|||||:..::...|.::.:::.
  Fly   104 HCWPYGEIF------------CQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKG 156

  Fly   167 AYSIIIFNWCL-----GALVALLPVFWNRWPDAQACEFDEVLAPGYIAGVITPGFVIIWIC---- 222
            ..:|:...|.:     |.||.....::|. ....|||      |.|    ..|.:.|:..|
  Fly   157 CVAILSLTWIISLTVFGFLVLPKGYYFNN-TGLMACE------PFY----SKPSYRILSTCALYF 210

  Fly   223 ---MFLVY----------WRI-----------------MREASKQALRLRQSVVYNTDEATTMRN 257
               |.|:|          :|:                 ....:.|.|::.|...::  :...|.:
  Fly   211 PTTMVLMYCYGSSFHMSRFRLNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHH--QQAGMHS 273

  Fly   258 LLLH-------------------------------------------PDW--KSVQIVVFI---- 273
            .|.|                                           |:.  |..:.:|.|
  Fly   274 HLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITKKIVPIQEKN 338

  Fly   274 --------MGCFTLCWL----PYFCVAIAQLFSICQSSS----MIYKTTFSLAIANSALNPIIYS 322
                    |...:|.::    |:   .|.::.:.|..|.    :.:..|:: |::||..||.:|.
  Fly   339 SSGSTSRSMAAISLGFIVMVTPW---TIQEIVTACTGSKLPPFLDFLVTWT-ALSNSLWNPFMYW 399

  Fly   323 WKNSGFRRAFVQTL----------------CC 338
            ..||.|||...|.:                ||
  Fly   400 LLNSDFRRMSRQLMPNKCFPHEDTPEHKSGCC 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	68/391 (17%)
		TM helix 1	53..78	CDD:410626	7/25 (28%)
		TM helix 2	86..111	CDD:410626	8/39 (21%)
		TM helix 3	123..153	CDD:410626	9/29 (31%)
		TM helix 4	166..185	CDD:410626	5/23 (22%)
		TM helix 5	204..229	CDD:410626	8/41 (20%)
		TM helix 6	261..291	CDD:410626	9/90 (10%)
		TM helix 7	300..325	CDD:410626	7/28 (25%)
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	43/201 (21%)
		TM helix 1	41..65	CDD:410626	6/23 (26%)
		TM helix 2	75..101	CDD:410626	6/25 (24%)
		TM helix 3	113..143	CDD:410626	9/29 (31%)
		TM helix 4	156..175	CDD:410626	3/18 (17%)
		TM helix 5	200..220	CDD:410626	5/19 (26%)
		7tm_GPCRs	<334..407	CDD:475119	17/76 (22%)
		TM helix 6	340..366	CDD:410628	4/28 (14%)
		TM helix 7	377..402	CDD:410628	7/25 (28%)