Protein Alignment mAChR-C and Dop2R

DIOPT Version :9

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001014758.2
• Gene: Dop2R / 33007
• FlyBaseID: FBgn0053517
• Length: 905
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 104/560 - (18%)
• Similarity: 162/560 - (28%)
• Gaps: 281/560 - (50%)

  Fly    31 NATETPTEITLQATSFGAGHLLWLAINAFLFVLILGGNILTIVAVRTCRHLRSV--ISNLFILSL 93
            |.|::..|:.:      ..|..|..|.....:|.|.||||.|::|  ||. ||:  ::|.||:||
  Fly   362 NLTDSCGELRV------VDHNYWALILILFPILTLFGNILVILSV--CRE-RSLQTVTNYFIVSL 417

  Fly    94 AVSDFCVG-LALPYHLVFYMGSDIGAMRGP-CLLRFFLLICACC--VSMLTLISIAVDRYIAVVY 154
            |::|..|. :.:|:.:.|.:.   ||...| .:..|::.:...|  .|:..|::|::||||||..
  Fly   418 AIADLLVAVVVMPFAVYFLVN---GAWALPDVVCDFYIAMDVICSTSSIFNLVAISIDRYIAVTQ 479

  Fly   155 ALHYRRYM-TRRVAYSIIIFNWCLGALVALLPVFW------NRWPDAQACEFDEVLAPGYIAGVI 212
            .:.|.::. :|||..:|::. |.:.|.:. .|:..      ||.||  .|.|       |.|..|
  Fly   480 PIKYAKHKNSRRVCLTILLV-WAISAAIG-SPIVLGLNNTPNREPD--VCAF-------YNADFI 533

  Fly   213 ----TPGFVIIWICMFLVYWRIMR----------------------------------------E 233
                ...|.|..|.|..:||.|.:                                        :
  Fly   534 LYSSLSSFYIPCIIMVFLYWNIFKALRSRARKQRAARKPHLSELTGGSVIENIAQTRRLAETALD 598

  Fly   234 ASKQALRL--------------------------------------------------------- 241
            :|:.|.|:
  Fly   599 SSRHASRILPDEAATNTASGSNEEEDENAISPDIDDCHVIVNDKSTEFMLATVVEETGNSVVAQI 663

  Fly   242 --------------------------------------------------------------RQS 244
                                                                          |.|
  Fly   664 TTQPQLVVADPNGNHDSGYAASNVDDVLAGVAPASASAATSAAPRSSGSPPDSPLPSGATLQRSS 728

  Fly   245 VV-------------------------------------YNTDEATTM-RN-------------- 257
            |.                                     |...||.|: ||
  Fly   729 VSSQRRPTGDDSPKRGEPALRSVGVDNSSVAMKPLSFVRYGVQEAMTLARNDSTLSTTSKTSSRK 793

  Fly   258 ------------LLLH-------------PDWKSVQIVVFIMGCFTLCWLPYFCVAI-----AQL 292
                        ..:|             .:.|:.:.:..::|.|..||||:|...|     |:.
  Fly   794 DKKNSQASRFTIYKVHKASKKKREKSSAKKERKATKTLAIVLGVFLFCWLPFFSCNIMDAMCAKF 858

  Fly   293 FSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRAF 332
            ...|:.....|..|..|...||.:||:||:..|..||:||
  Fly   859 KKDCRPGLTAYMMTTWLGYINSFVNPVIYTIFNPEFRKAF 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	96/528 (18%)
		7tm_1	67..321	CDD:278431	89/511 (17%)
Dop2R	NP_001014758.2	7tmA_D2-like_dopamine_R	376..>565	CDD:320181	62/205 (30%)
		TM helix 1	377..403	CDD:320181	11/27 (41%)
		TM helix 2	410..436	CDD:320181	9/25 (36%)
		TM helix 3	448..478	CDD:320181	10/29 (34%)
		TM helix 4	490..513	CDD:320181	7/24 (29%)
		TM helix 5	529..558	CDD:320181	9/28 (32%)
		7tm_GPCRs	<822..898	CDD:333717	23/75 (31%)
		TM helix 6	825..850	CDD:320095	8/24 (33%)
		TM helix 7	866..891	CDD:320095	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840