Protein Alignment mAChR-C and Taar7b

DIOPT Version :9

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_783176.2
• Gene: Taar7b / 294126
• RGDID: 631392
• Length: 358
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 81/308 - (26%)
• Similarity: 135/308 - (43%)
• Gaps: 46/308 - (14%)

  Fly    51 LLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVGL-ALPYHLV----- 109
            |:..|:..|..||.:.||:|.:.::...|.|.|. :|..:.|||.:||.||| .:|:.:|
  Rat    48 LILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSP-ANFLVASLACADFLVGLTVMPFSMVRSVEG 111

  Fly   110 -FYMGSDIGAMRGPCLLRFFLLICA---------CCVSMLTLISIAVDRYIAVVYALHYRRYMTR 164
             :|.|.               :.|.         |..|:..|..|:.||||||...|.|....|.
  Rat   112 CWYFGD---------------IYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTA 161

  Fly   165 RVAYSIIIFNWCLGALVALLPVFWNRWPDAQACEFDEVLAPGYIAG---VITPGFVIIWICMFL- 225
            .|:...|.|:|.| :::....:|:....:| ..| |.|.|...:.|   .:...:|.|...:||
  Rat   162 SVSGKCITFSWLL-SIIYSFSLFYTGVNEA-GLE-DLVSALTCVGGCQIAVNQSWVFINFLLFLV 223

  Fly   226 -------VYWRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLP 283
                   ||.:|...|.:||..:.:........:.:.::.:...:.|:.:.:...:..|.|.|||
  Rat   224 PALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLP 288

  Fly   284 YFCVAIAQLFSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRA 331
            ||..:|...|....:.:.:|:....:...|||:||:||::....||:|
  Rat   289 YFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKA 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	78/298 (26%)
		7tm_1	67..321	CDD:278431	71/280 (25%)
Taar7b	NP_783176.2	7tm_GPCRs	49..337	CDD:421689	80/307 (26%)
		TM helix 1	49..75	CDD:410628	7/25 (28%)
		TM helix 2	82..108	CDD:410628	11/25 (44%)
		TM helix 3	120..150	CDD:410628	10/29 (34%)
		TM helix 4	162..185	CDD:410628	6/23 (26%)
		TM helix 5	209..238	CDD:410628	7/28 (25%)
		TM helix 6	266..296	CDD:410628	9/29 (31%)
		TM helix 7	305..330	CDD:410628	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24249
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010