Sequence 1: | NP_572358.1 | Gene: | mAChR-C / 31626 | FlyBaseID: | FBgn0029909 | Length: | 371 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001239571.1 | Gene: | Hrh1 / 15465 | MGIID: | 107619 | Length: | 488 | Species: | Mus musculus |
Alignment Length: | 474 | Identity: | 94/474 - (19%) |
---|---|---|---|
Similarity: | 159/474 - (33%) | Gaps: | 182/474 - (38%) |
- Green bases have known domain annotations that are detailed below.
Fly 44 TSFGAGHLLWL-AINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALPY 106
Fly 107 HLVFYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSII 171
Fly 172 IFNWCLGALVALLPVFWNRW----PDAQ--ACEFD-------EVLAPGYIAGVITPGFVIIWI-- 221
Fly 222 ---------CM-----------FLVY-------------------WRIMREASK----------- 236
Fly 237 ----------------------------------------------------------------- 236
Fly 237 --------QALRLRQSVVYNTDEATTMR-----------------------------------NL 258
Fly 259 LLHPDWKSVQIVVFIMGCFTLCWLPYFC--VAIAQLFSICQSSSMIYKTTFSLAIANSALNPIIY 321
Fly 322 SWKNSGFRRAFVQTLCCRT 340 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
mAChR-C | NP_572358.1 | 7tm_4 | 61..332 | CDD:304433 | 87/446 (20%) |
7tm_1 | 67..321 | CDD:278431 | 82/429 (19%) | ||
Hrh1 | NP_001239571.1 | 7tmA_Histamine_H1R | 29..480 | CDD:320178 | 88/455 (19%) |
TM helix 1 | 29..55 | CDD:320178 | 7/25 (28%) | ||
TM helix 2 | 62..88 | CDD:320178 | 10/25 (40%) | ||
TM helix 3 | 100..130 | CDD:320178 | 7/29 (24%) | ||
Important for agonist binding. /evidence=ECO:0000250 | 107..112 | 1/4 (25%) | |||
TM helix 4 | 142..163 | CDD:320178 | 5/20 (25%) | ||
TM helix 5 | 187..216 | CDD:320178 | 3/30 (10%) | ||
TM helix 6 | 218..439 | CDD:320178 | 25/220 (11%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 245..337 | 2/91 (2%) | |||
Important for agonist binding. /evidence=ECO:0000250 | 425..429 | 2/3 (67%) | |||
TM helix 7 | 448..473 | CDD:320178 | 9/24 (38%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C167834922 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.930 |