| Sequence 1: | NP_572358.1 | Gene: | mAChR-C / 31626 | FlyBaseID: | FBgn0029909 | Length: | 371 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000666.2 | Gene: | ADORA2A / 135 | HGNCID: | 263 | Length: | 412 | Species: | Homo sapiens |
| Alignment Length: | 346 | Identity: | 101/346 - (29%) |
|---|---|---|---|
| Similarity: | 151/346 - (43%) | Gaps: | 53/346 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 49 GHLLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALPYHLVFYM 112
Fly 113 GSDIGAMRGPCLLRFFLLICACCVSMLT------LISIAVDRYIAVVYALHYRRYMTRRVAYSII 171
Fly 172 IFNWCLGALVALLPVF-WNRWPDAQ--------------ACEFDEVLAPGYI------AGVITPG 215
Fly 216 FVIIWICMFLVYWRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLC 280
Fly 281 WLPYFCVAIAQLFSICQSSSMIYKTTFSLAI----ANSALNPIIYSWKNSGFRRAFVQTLCCRTA 341
Fly 342 RQCEDQLPADSKHRMEATSSS 362 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| mAChR-C | NP_572358.1 | 7tm_4 | 61..332 | CDD:304433 | 92/302 (30%) |
| 7tm_1 | 67..321 | CDD:278431 | 86/285 (30%) | ||
| ADORA2A | NP_000666.2 | 7tmA_Adenosine_R_A2A | 7..299 | CDD:320196 | 92/312 (29%) |
| TM helix 1 | 8..34 | CDD:320196 | 7/25 (28%) | ||
| TM helix 2 | 41..68 | CDD:320196 | 11/26 (42%) | ||
| TM helix 3 | 77..107 | CDD:320196 | 14/29 (48%) | ||
| TM helix 4 | 121..139 | CDD:320196 | 6/17 (35%) | ||
| Agonist binding | 168..177 | 2/8 (25%) | |||
| TM helix 5 | 174..204 | CDD:320196 | 9/34 (26%) | ||
| TM helix 6 | 226..256 | CDD:320196 | 12/33 (36%) | ||
| Agonist binding | 246..253 | 3/6 (50%) | |||
| Agonist binding | 264..274 | 1/9 (11%) | |||
| TM helix 7 | 267..292 | CDD:320196 | 9/24 (38%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 391..412 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D252862at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||