Protein Alignment mAChR-C and adora3.2

DIOPT Version :9

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_002932849.3
• Gene: adora3.2 / 100496301
• XenbaseID: XB-GENE-982271
• Length: 313
• Species: Xenopus tropicalis
• Alignment Length: 336
• Identity: 99/336 - (29%)
• Similarity: 157/336 - (46%)
• Gaps: 68/336 - (20%)

  Fly    32 ATETPTEITLQATSFGAGHLLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVS 96
            |.||....|..|...|...:  :.|:|.|      ||||.|.|||....|::. :..||:|||::
 Frog     4 ANETSDAATYAAVYIGVETV--IGISAVL------GNILVIWAVRLNPSLQTT-TFYFIVSLALA 59

  Fly    97 DFCVG-LALPYHLVFYMGSDIGAMRGPCLLRFFLLIC--ACC-------VSMLTLISIAVDRYIA 151
            |..|| |.:|..:|..:|           :.|...:|  .||       .|:|:|::||:|||:.
 Frog    60 DLAVGFLVMPLAIVLSLG-----------IHFHFHVCLFICCFIIVLTNASILSLLAIAIDRYLR 113

  Fly   152 VVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVF-WN----------RWPDAQACEFDEVLAP 205
            :.....||...|||:..|:.|. |.:..||.::|:| ||          .:.|   |.|:.|::.
 Frog   114 IKIPTRYRTVTTRRIGLSVCIV-WIISFLVGMVPMFGWNNRFSLNEEHQHYLD---CTFENVMSK 174

  Fly   206 GYIAGVITPGFV----IIWICMFLVYWRIMREASKQ--ALRLRQSVVYNTDEATTMRNLLLHPDW 264
            .||......|:|    ||.:.:::..:|::|:..||  ....::.|.|..:..|.
 Frog   175 EYIINFYVSGWVFLPLIIMLILYIEIFRLLRKQLKQNPTNYAKKGVFYGKEYKTA---------- 229

  Fly   265 KSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAI----ANSALNPIIYSWKN 325
            ||:.:|:.:   |.|.|||...:...|.::.......:|:.|..|.|    ||||:|||||::|.
 Frog   230 KSLALVLLL---FALSWLPLAILNCVQFYNPNVKKLGLYQPTIFLFILLSHANSAMNPIIYAFKI 291

  Fly   326 SGFRRAFVQTL 336
            ..|:.|::..|
 Frog   292 KKFKEAYIHIL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	88/301 (29%)
		7tm_1	67..321	CDD:278431	84/284 (30%)
adora3.2	XP_002932849.3	7tm_GPCRs	15..298	CDD:421689	93/319 (29%)
		TM helix 1	16..42	CDD:410628	12/33 (36%)
		TM helix 2	49..76	CDD:410628	11/26 (42%)
		TM helix 3	85..115	CDD:410628	11/29 (38%)
		TM helix 4	128..146	CDD:410628	5/18 (28%)
		TM helix 5	174..204	CDD:410628	7/29 (24%)
		TM helix 6	223..253	CDD:410628	9/42 (21%)
		TM helix 7	266..291	CDD:410628	12/24 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920