Protein Alignment mAChR-C and adora2a

DIOPT Version :9

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001106398.1
• Gene: adora2a / 100127551
• XenbaseID: XB-GENE-970783
• Length: 392
• Species: Xenopus tropicalis
• Alignment Length: 344
• Identity: 96/344 - (27%)
• Similarity: 153/344 - (44%)
• Gaps: 59/344 - (17%)

  Fly    51 LLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALPYHLVFYMGS 114
            |:::.:...:.||.:.||:|...||....:|::. :|.|::|||.:|..|| ||:|:
 Frog    13 LVYIVLEVAIAVLSILGNVLVCWAVCINSNLQNA-TNYFVVSLAAADIAVGVLAIPF-------- 68

  Fly   115 DIGAMRGPCLLRFFLLICACCVSMLT------LISIAVDRYIAVVYALHYRRYMTRRVAYSIIIF 173
            .|....|.|......|..||.|.:||      |::||.|||||:...|.|...:|.|.|.:||..
 Frog    69 AIAISTGFCATFHACLFIACFVLVLTQSSIFSLLAIAADRYIAIRIPLRYNSLVTSRRANAIIAV 133

  Fly   174 NWCLGALVALLPVF-WN-----------RWPDAQACEFDEVLAPGYI------AGVITPGFVIIW 220
            .|.|..::.|.|:. |:           |.|..: |.|:.|:...|:      |.|:.|     .
 Frog   134 CWLLSFVIGLTPMLGWHKEVPPSGNTTCRSPMIE-CLFENVVTMDYMVYYNFFACVLIP-----L 192

  Fly   221 ICMFLVYWRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYF 285
            :.|..:|.||...|..|..:::..|.......:|::.     :..:.:.:..|:|.|.|||||..
 Frog   193 LLMLGIYLRIFMAARHQLKQMKMKVTCGERSRSTLQR-----EVHAAKSLAIIVGLFALCWLPLH 252

  Fly   286 CVAIAQLFSICQSSS----MIYKTTFSLAIANSALNPIIYSWKNSGFRRAFVQTLCCRTARQCED 346
            .:....||  ||:.:    .|..|...|:.|||.:||:||:::...||..|.:.|        ..
 Frog   253 IINCFTLF--CQACNRPPLWIMYTAILLSHANSVVNPLIYAYRIREFRHTFRKIL--------HQ 307

  Fly   347 QLPADSKHRMEATSSSQEI 365
            .|.....|....|:|:..:
 Frog   308 HLFGQGPHLKTRTASANSL 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	89/299 (30%)
		7tm_1	67..321	CDD:278431	83/282 (29%)
adora2a	NP_001106398.1	7tmA_Adenosine_R_A2A	13..301	CDD:320196	90/309 (29%)
		TM helix 1	14..40	CDD:320196	7/25 (28%)
		TM helix 2	47..74	CDD:320196	12/34 (35%)
		TM helix 3	83..113	CDD:320196	14/29 (48%)
		TM helix 4	127..145	CDD:320196	6/17 (35%)
		TM helix 5	176..206	CDD:320196	8/34 (24%)
		TM helix 6	228..258	CDD:320196	8/34 (24%)
		TM helix 7	269..294	CDD:320196	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920