DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nonC and smg1

DIOPT Version :9

Sequence 1:	NP_001284967.1	Gene:	nonC / 31625	FlyBaseID:	FBgn0263968	Length:	3218	Species:	Drosophila melanogaster
Sequence 2:	XP_002932267.3	Gene:	smg1 / 100145499	XenbaseID:	XB-GENE-489705	Length:	3653	Species:	Xenopus tropicalis

Alignment Length:	3907	Identity:	996/3907 - (25%)
Similarity:	1593/3907 - (40%)	Gaps:	1009/3907 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NGAGTEEEASSAFHAEIDRVLLNNNGNHGDSSNEGGGGNGSGR---GGATGSGNIAGLGGSESMW 72
            |.||...:.......:.|   :.|....|.|.|.|.|.:..||   |......|:
Frog    57 NSAGLTRQKHDDIRVQAD---VQNEEEDGYSVNGGSGESAFGRKSLGQELRVNNV---------- 108

  Fly    73 SPGGGKSHDVAQAFANALLLRNMNHVVGKGQPVVQNHRKAYQCKGDTINPMANGEDLRLSKIIRR 137
            ||    .....|....||..::|..        :|:...:|            .::.|||.::||
Frog   109 SP----DFTTVQHGNRALASKDMRK--------LQDRSLSY------------SDESRLSNLLRR 149

  Fly   138 LINENNPTVSLELCSKLDQAVRTPIN---MGYMTCSFVWILDNMLTLYKQCPPPVLEECSK---- 195
            :..|::....|....:|.:.::.|.|   :|..       |||:||....    ||.|.||
Frog   150 ITREDDRDRRLATVKQLKEFIQQPENKMVLGKQ-------LDNILTAIND----VLNESSKLLQE 203

  Fly   196 -------TLGLI-GFINRKSYPIYEEFIVKNYKSSKRMQKYMIMALRATLSCDTKCELHMYADK- 251
                   .|||: ..::.::..|::....|...|||...|.:.:       |.|...|....:|
Frog   204 LRQEGAQCLGLLCASLSYEAEKIFKWVFSKFSSSSKDEVKLLFL-------CSTYKALETVGEKK 261

  Fly   252 --------IMLLLKDFLENAESADIFIVVSNTLVQFAASYAETFECHFTDVVDIVIGWQLEAGQP 308
                    :|..|:..|||.::.::.......::..:..|...|..:|.|.|||::||.::..|.
Frog   262 AFSSVMQLVMTSLQSILENVDTPELLCKCVQCILLVSRCYPHIFSTNFRDTVDILVGWHIDHTQK 326

  Fly   309 TDLKTHCAQVLEQLTPFFSKQIDFSYGLLDQFVEDITTLEE-------GE--------PANTAER 358
            ..|....:..|:.|.||:...:.||..||.||:||:....|       ||        |:.:..:
Frog   327 ASLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLGHVASGESVDEDIPPPSVSLPK 391

  Fly   359 VGAFVGAFNTLLKCLA-RMQIFVGMPTCECIVKMAVDHLIKIMPTLH-----LNTEA-LVNINEL 416
            :.|.:..|:|:::.:. |.....|.|..|..|.   |.|.::|..:.     .::|| |...||.
Frog   392 LAALLRVFSTVVRSIGERFSPIRGPPITEAYVS---DILFRVMRCVTAANQVFSSEAVLTAANEC 453

  Fly   417 ICICLLNNFTGLDPIL---LEQVL---LDQVKRMISLTELQRQSVLYLLLCTVRRLRARLTPSLV 475
            :.:.|    ..:||.:   .:.|:   |||::...:.......|||.||...|.::..:|..:.|
Frog   454 VGVLL----GSMDPSMATHCDIVITYGLDQLENCQTSGTDYIISVLTLLTLIVEQINTKLPATFV 514

  Fly   476 HFIFQSNPYMTKVRLRSPGE------TSYKLLLRTCQETLLIRNVPLLQQAYKYLVDDIDACLEK 534
            ..:|.....:..:|.....|      |.|       |..|.::|:|:|:.|||.::.::...|..
Frog   515 ERLFVPESKLLALRNHKEKEVIGAAHTVY-------QAVLTLKNIPVLETAYKLILGEMTCALNS 572

  Fly   535 LL--ITAPRS--------------KARKASVLLVFHLSALAALAKQTSSIIGMYACKPSILELLL 583
            ||  :..|.:              ....|:.:::|.||.|..:....:|:|||:|..|::..||.
Frog   573 LLHCLHLPEACTEIQHEAFRNHVFTVDSATFVVLFDLSVLTTIGNAKNSLIGMWALSPTVFALLS 637

  Fly   584 TNCRAHELKFWSKYPAAQQAIFGLLVVHCQANHNF-----RTNSSLLRDQELSAENTSPTANSFA 643
            .|...........|||.|.::...|..||..:.:|     .::|..|.|..:.:..|:.|...|:
Frog   638 KNLIIVHEDIAIHYPAIQYSVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFS 702

  Fly   644 SILRFLDSVLGQAHQLAPQNLRVLLQW---IQMLLRECREKIDLLMEQENFRGICRNIAA-TASK 704
            .||..|.::| :...|...:.::|:.|   :.:|::: .|....|....:|...||.:.| |..:
Frog   703 IILNLLGTLL-KKDNLNQDSRKLLMVWASEVAVLMKK-SETYAPLFSLPSFHVFCRGLLANTLFE 765

  Fly   705 LVPLESAACIQT-VLDYGLERLEKYPKLLILYRDTALQQLQMLSTNYHAPYFQIYAQLPLHLTLT 768
            ...:...||... :|...|..     .||....|....||....|.....:.::...:.|...|:
Frog   766 DANISLQACSSLHILSSSLPE-----DLLQRCVDVCRVQLVSSGTRVRQAFGKLLKSISLDFVLS 825

  Fly   769 GGESSMPGMASRRVSVWQQRISQYSAVRD-------NVF--RDFFDRVQ-----KPEQDSLIHCL 819
            ...::.           .|.||  ||:|:       |.|  :||.|.:.     ...:....:.|
Frog   826 NTNNTE-----------MQEIS--SAIRNHMSKSPSNTFHQQDFSDVISFILYGSSHRSGKENWL 877

  Fly   820 RELFVRSCQVAPQDERQMN-LSQCTKRCQRLAIAWLQFEAARYCVDQRLRTTVGKPQETFLGFEA 883
            ..||   |.....|:|.:: :.:...:...:...|..:|||::.|..:|||.:|:.|:||...|.
Frog   878 ERLF---CSCLRLDKRDVSPIPRNLLKTDAVLWQWAVWEAAQFTVLSKLRTPLGRAQDTFQTIEG 939

  Fly   884 IIMRHARLLSGCAKEIER--SALDDLSLEELLSMQSNLSLLLGFLDALEKLIYNAAEGSAFALRP 946
            ||...|.......:::.:  ||.:|   |...:.|..|.|||.:|:.|:||:|||.||.|.||..
Frog   940 IIRSLAAHTLNPDQDVGQWTSADND---EGHGNNQLRLVLLLQYLENLDKLMYNAYEGCANALTS 1001

  Fly   947 PEKQVAAFFRLNNPTCQSWFNRIRIGVVIIAMHVQQPELVIRYAQQILV----NSKTQDPTYSQA 1007
            |.|.:..||..|..|||.|..|||:.::.:.:...||.:.:|:...:|.    |:..|...:...
Frog  1002 PPKVIRTFFYTNRQTCQDWLTRIRLAIMRVGLMAGQPAVTVRHGFDLLTEMKNNNTPQGTEFELT 1066

  Fly  1008 IVYMAWSLVSCQEADSLRGLRLWARGKSCKSYKWLKYAADQAAGKRESALAGY------------ 1060
            ::.:..:|...|..::::||.:|:...:.||..|:...|..|.|:.|.|...|
Frog  1067 VMMVVEALCELQCPEAIQGLAVWSSAVAGKSLSWISSVALHADGRFEKAAVEYQEHLCAMTGVDC 1131

  Fly  1061 ------------------------------RTILAEKELQSELEPHTRQFVVSQMMQCLQDLGQW 1095
                                          :|:|.:   .|:..|....::.::..:|...:..|
Frog  1132 STSGFDKSVLKLANATGNSASPKHSNGDARKTVLTK---PSDPVPEVINYLGNKACECYIAIADW 1193

  Fly  1096 SQLVELKQQQMTRPEDRELNPFLQRSNVEVNALERLLAKSE----ESCSSMDA--LGGVFQQLSL 1154
            :.:    |:.....:|.:..|    |.:.||      .|::    :|.||.::  |....:||.|
Frog  1194 TAV----QEWQNSMQDLKKGP----SGICVN------LKADFNYIKSLSSFESGELLECTEQLEL 1244

  Fly  1155 WPSNWDESVSSSGLSERASFSSIHMRQRTEDIVLHKLLEDRCVPD--QAKNLLDTQ-WRDSL--- 1213
            .|.. :.::.|.|..|:              |.:.|||.:...||  :.:..::.| .|.|:
Frog  1245 LPGE-NLNLLSGGTKEK--------------IDMKKLLPNMLSPDPRELQKCIEIQLLRSSVCFS 1294

  Fly  1214 --LNPSFDQRSCKELT-----LLRHIVQGVSGGQELSLLPVSS-----GRCQNRSKFISSAI--- 1263
              ||....::..:..|     .|:...:...|...||.|.:|.     |..|   .:.|||:
Frog  1295 LALNEQDQEQKWQATTENLSKYLKQTARTAMGPLRLSTLTISQYLPMLGTLQ---LYCSSALEST 1356

  Fly  1264 ------------------LMRC-----LAWTQLLR----QHCAPGSWE-----------TLCLDA 1290
                              |..|     ..|...||    |:......:           .|.|.|
Frog  1357 VSSKLSSEDCLIPLFSEALRLCKQHDVRPWIHALRYTVFQNTITDKLKDQTVSVKSHLMELGLTA 1421

  Fly  1291 AAAAREEGNLQLAETLLTQFFGQPIGEIAALFSLE--------QGVQTD---NPEMLRGYSELVK 1344
            |..:|:.||:.||..||.|.....:.::.....|.        || |.|   .|||   ..|..|
Frog  1422 AKCSRKRGNVTLATRLLAQCSDIQLIQVTNAQDLVNHFKKLSIQG-QMDEKWGPEM---DIEKAK 1482

  Fly  1345 CLHLQQQQSQTHSGDLSSSIDVCAALCLNIQKSNNQPAAGADLLLNLADWIAV--RTCNG----- 1402
            .|::..|  .||:.::.||   ||   ::..||.....|.|..:|.||.||..  :..:|
Frog  1483 LLYVAGQ--STHAMEMLSS---CA---ISFCKSAKAEYAVAKSILTLAKWIQAEWKEISGQIKQV 1539

  Fly  1403 -LTTNQSPV---------LIQLLDQLP------ECP-LTCDSSQPLAIPQAERMVARLVHSCLQQ 1450
             ....||.|         :..|:|..|      |.| :..:|:..:.:.:.:.::.:|.|....|
Frog  1540 YRARQQSNVSSLSTLGKNIYTLIDLPPVNAMDEEYPQIESESTVSIGVGEPDFIMGKLYHLSSVQ 1604

  Fly  1451 RPNYAEALIAYGNWCYRWGKKVADSC-----CVLTQADATAI--------------------SQA 1490
            .|..|::..|..:|.||||:||.|:.     ..|.|.:.:.:                    .||
Frog  1605 APEVAKSWAALASWAYRWGRKVVDNASQGEGVKLLQREKSEVQTLLPDNVSEEDKEKIFGILGQA 1669

  Fly  1491 LDIPQPLESEKLDELLQALSTEQPPANCVEVCPDAARARDDEAAKNRLRRLTFLADKTPEALDAI 1555
            :..|..::.|  |..||....|....|.:|          |...:..|....:|||...:|.:.:
Frog  1670 MCRPAGIQDE--DISLQITENEDNDENNME----------DVIWRQLLASCPWLADLEEKASEGL 1722

  Fly  1556 LQIWRRAIANTYDYYKDAARSYFQYLSFKSGSGPEKPEGEGVVSQRE---RLHVD-------DSN 1610
            :::|::.:...:..||.:..:||.:|...:|.          ||..|   |||::       |..
Frog  1723 IKLWKKVVDRIFSLYKLSCSAYFTFLKLNAGR----------VSLDEDDPRLHLNIPSKQSTDDV 1777

  Fly  1611 LVTTTLRLLRLIVKHASGLQEVLEQGLHTTPIAPWKVIIPQLFSRLNHHEPYVRKSVCDLLCRLA 1675
            :|..|||||||:||||..|::.|||||.|||.|||:.|||||||||||.|.|||:|:|:||||:|
Frog  1778 IVMATLRLLRLLVKHAGELRQYLEQGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVA 1842

  Fly  1676 KSRPQLVIFPAVVG----ANREQQDAT--------------------------APPAT------- 1703
            ...|.|:::||:||    :|..|...|                          :|||:
Frog  1843 HDSPHLILYPAIVGSISLSNESQSSGTKLSSAIPTLLGNIQDDELMGVEGEEGSPPASQESKDEL 1907

  Fly  1704 ARPTTEDAC----CYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSR 1764
            .....||..    ||..::.:||...|..|..|:::|.|||||.:||||.|:..|...:...:.|
Frog  1908 KNALNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRR 1972

  Fly  1765 VSALATDFRPDDHEG---KNNRFNVWRPQ-------LLADLEALVAVTSRPPETTYERSFRKRFD 1819
            :..|..:.:...:..   |..:..:.|.:       ::..||.:.::||.|.||.:|:.|:..:.
Frog  1973 IQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVCSITSAPSETPHEKWFQDTYG 2037

  Fly  1820 APIRLTVDALRHRRYP----EAWDKLKQLYHILQSNMIRGSGSTLKMQSISPVLCGIGRMRISMP 1880
            ..|...::.||:...|    .:|...||:...||....:.:...|:::.|||.|..:....|::|
Frog  2038 EAIGNALEKLRNPSNPANPGNSWMPFKQIMLSLQQRAQKRASYLLRLEEISPCLTAMTNTEIALP 2102

  Fly  1881 GLDAHGPDGDQVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSI 1945
            |   ...|.|.:.|.||.|::.:|||||||||..|.||:|:.|.:||||:|||||||||||||||
Frog  2103 G---EVSDRDTITIHSVGSNITILPTKTKPKKFIFLGSDGKNYPYLFKGLEDLHLDERIMQFLSI 2164

  Fly  1946 SNAIMAC--RSDAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVAGNAGA 2008
            .|.:.|.  ..::|.   :.|.||||.|||.:||||.||||.||:|.|||:||||.:.:......
Frog  2165 VNTMFATINSKESPH---FHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQ 2226

  Fly  2009 GAV------ANVPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLLQVLDELSQETPNDLLAR 2067
            .:.      |.|||. ::|:|:|:||.|....:.:...||.||::|:..||:||.:.||.:|||:
Frog  2227 DSYQTPQNPAMVPRP-SELYYSKISPALKAVGLSLDVSRRDWPLNVMKSVLEELMEATPPNLLAK 2290

  Fly  2068 ELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGR 2132
            ||||...:..||.:..:.:.|..:||||:||:|||||||||||||::.:|::||||||||||||:
Frog  2291 ELWCSCASPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGK 2355

  Fly  2133 TLRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTTN 2197
            :||:|||||||:|||:..|:|:||:||.|||.||.||.:||:.||||||||||||||||||||..
Frog  2356 SLRVPEKVPFRMTQNIECALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAG 2420

  Fly  2198 DDAQALRRSLNAKLQESADGGGAGGL--GVGDLKYHKKDKNKGKPLDSDVKRQPFLSKLGMLQKY 2260
            .:|                 |.||.:  |.|.....|:.|   :.::.::.:..|.|::..::..
Frog  2421 GEA-----------------GFAGAVYGGGGQQAESKQSK---REMEREITQSLFSSRVAEIKVN 2465

  Fly  2261 WSTNKTEL---MPQLEEMEQEVGNLQAAQAKQVVAEEELVKLNQ-RSALIAEIKSL-GTAIESHS 2320
            |..||.|:   :|:|:...:|..||          .|||:.:.: ::.|:.|::.| |.....|.
Frog  2466 WFKNKEEMLSVLPKLDTSLEEYLNL----------HEELMDVEKLQTKLMEEMEFLEGAESTEHP 2520

  Fly  2321 FNTASLRNAVRRGHSEALALLSTERLPDFGRVQCILRSYGQCLQLYHLL--DLQG-QLVKLQMES 2382
            .:|...|.:   .|::    |.|::......:|..|..:.|.:..|...  :|:. ||..|..|.
Frog  2521 SHTLQHRFS---EHTQ----LQTQQRAVQEAIQVKLNEFEQWITQYKTAFGNLEATQLAGLLQEI 2578

  Fly  2383 NS----------------ENAREFSALTEALQLSGLDSMRSQLNELLGRMDMVAQKSSKHLQEYA 2431
            :|                :||.:...:|:.      :...:::..||.:...|.:...:||..||
Frog  2579 SSPMDLGPPSYVPATAFLQNAGQAHLITQC------EQYEAEVGALLQQRRSVLRACLEHLHNYA 2637

  Fly  2432 GVMNFYPE---QSHR--------------------QNLFVRFHDSFA--------TYIQ------ 2459
            .|...||:   |.||                    |.|:.::...:|        .:|.
Frog  2638 TVALLYPKAVFQKHRIEQWKTWMEELICNMTMEHCQELYRKYEMQYAPQPPQPLCQFISATEMAL 2702

  Fly  2460 NGYTADSTTNTNSPSSSIICKADVVGVAEAMEYSWER-LGCQLHE-------------ASKLYAA 2510
            ..|..|...........:..:|..:.|.|......|| :...|||             .|.|.|.
Frog  2703 QRYAGDINNRLLRQVDRLKQEAVSLPVCEDQLKEIERCIKVFLHENKEEGCLSLASVVISALCAL 2767

  Fly  2511 NQAQALTLGAPTTA---LLSMIVQSG-------CS---------QLLLKASLV-RTLDRAGGAFA 2555
            .:...:..||.::|   |:.:..:.|       ||         |||.:..|| :.|| ......
Frog  2768 TRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCQLVPQDLD-IPNPTE 2831

  Fly  2556 AYEQVALASHDDGLL---------HHQLLFIHLVRTMLQGVLV---MTKEEDQHLAQ-------- 2600
            |||.|.||   :|:.         ..|::|...:|.:::|...   |.:|.|..:.|
Frog  2832 AYEAVHLA---NGVYISLQELNSNFRQIIFPEALRCLMKGEQTLENMLQELDNLIEQSTDGATLQ 2893

  Fly  2601 --LESLLSALSHLKKMFEYDLPA---NLYRLL------LLQPNLGKLSALCHLSASSLAQLFLEA 2654
              :|||.:.|.:.....|.:..|   ::.|||      |:||..|.:.....:||   .|:.|.|
Frog  2894 TLVESLQTYLRNAAMGLEDEANAHYIDIARLLHSQYGDLIQPRNGSVEETPKMSA---GQMLLVA 2955

  Fly  2655 TMENGHKPPDQFPVERRFLLTLQPVYD-QFLLASTSLDSLVSSMQSM-----------LEDVHDV 2707
                                     :| .|....|:..|||..::.|           :.:....
Frog  2956 -------------------------FDGMFAQVETAYGSLVEKLKKMEVPQAWRKVDIIREARST 2995

  Fly  2708 QTQQIMELGLMRSCHTELNDECFF--------------GLVSEALESSRTCDVR----------- 2747
            |.....:.||.|     :.||.||              |:.|:.|  |..|.:.
Frog  2996 QVNFFDDDGLQR-----VLDEIFFLKRLQTIREFFRLCGIFSQTL--SGKCSLEDQNTVNGPMQM 3053

  Fly  2748 ---------------EMARPMLGFIHRLQVEKLAGL----LPILTRNFYTAVGPQCLPTASCGD- 2792
                           :|::|:.||......:.|.||    |.:...:|.:|:|...:......|
Frog  3054 VNVKTMYRNACISEDQMSKPIKGFTADFVRQLLIGLPTQALGLTLCSFISALGVDIIAQVEAKDF 3118

  Fly  2793 ----PAQADHLCESLF---ISLQSDGALLQQQAEIALLS-------------------------Q 2825
                ....|.|.:...   :.|.....|:..:|.:...|                         |
Frog  3119 GAESKVSVDDLHKKAVDQNLHLNRFSQLVMNRATVLASSYDTAWKKQDLVRRLETNIAACKTSLQ 3183

  Fly  2826 QVDLHTLAASAQY-WAYSEALGSQLRCGPHIVSRPK------------LTA------AIGECWLE 2871
            :|.||.    |.: |.:.:.|          ::||:            ||:      .:|    :
Frog  3184 RVQLHI----AMFQWQHEDFL----------INRPQTLSVTPPPRSAILTSMKKKLHTLG----Q 3230

  Fly  2872 LDQKLTALQQLQAGLESQLSQ---------------LQ------TQRSNW----NRN-------- 2903
            :|..:..:|:..|.||:.:.|               ||      |:|.|.    |:.
Frog  3231 IDSSIVTVQEKLAALEASIEQRLKWAGGANPALAPVLQDFEATITERRNLVLKENQRINQVTFLC 3295

  Fly  2904 ----HIDNLLRMEQCNKQRTMSHVAL----------LQKMTDGA----GAVARLEQNAIV-VGEE 2949
                |.:.|       :.||...::|          .|:|...|    .:|:.||...:. ||..
Frog  3296 STIIHFEGL-------RTRTTETLSLDASLFELIKRCQQMCSFASQFNSSVSELELRLLKRVGTS 3353

  Fly  2950 GQALVDHLEQWLAAHGQWQASSSRISAVE-------QSMVELLDPEGAID---------HYWLEN 2998
            .:..:...|..::||.|.....|...:::       :::.||:  :..:|         :..|.:
Frog  3354 SEHAIGSPEWLVSAHKQLSNDMSNQRSLQGEKEQQIETVCELI--QNLVDSIKNILTGHNRQLGD 3416

  Fly  2999 VQGLLEEQTCKVHREIAAIEGE----QQSKHRFICTLLKETLRLLENMPRFHVQS-LCSEAQAQG 3058
            |:.||:...  ...|.|..:||    :.|..:|:|    |.....:|     :|: |.:..||.|
Frog  3417 VKHLLKAMA--KDEEAAMADGEDVPYENSVRQFLC----EYKSWQDN-----IQTVLFTLVQALG 3470

  Fly  3059 QGKMEYANVQLLSD---HLREGQGLMQSLYMRLQELRKDICSDRR-------------------- 3100
            |.:.: .::::|.:   .|:|.:...||:|..|......:.:|..
Frog  3471 QVRSQ-EHIEMLQEITPTLKELRNQSQSIYNNLVSFASPLVTDATNECSSPTTSSTYLPSFAAAV 3534

  Fly  3101 ------VLQP-SMLQNWRHQLE------------MILTLAKQEVNEFFKGLEDFMQHAGETDSYE 3146
                  ..|| .|.||.:..::            .:|...|..|:...|.:.|  ...|:.
Frog  3535 RSNTVPKTQPEGMSQNTKKPVQRNLATSADTPPSAVLGPGKNVVSSPKKAVRD--PKTGKA---- 3593

  Fly  3147 IFTHAKGSGNVHEQKRNAYGVSVWKKIRMKLEGRDPDSNQRSTVAEQVDYVIREACNPENLAVLY 3211
                        .|:||:|.|||||:::.||||||.|.|:|.:||||||:||:||.|.||||.||
Frog  3594 ------------VQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDFVIKEATNLENLAQLY 3646

  Fly  3212 EGWTPWV 3218
            ||||.||
Frog  3647 EGWTAWV 3653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonC	NP_001284967.1	SMG1	571..1140	CDD:292413	147/645 (23%)
		Rapamycin_bind	1738..1845	CDD:285924	31/120 (26%)
		PIKKc_SMG1	1894..2196	CDD:270714	175/309 (57%)
		FATC	3189..3217	CDD:280430	21/27 (78%)
smg1	XP_002932267.3	DUF5303	28..134	CDD:407346	21/101 (21%)
		SMG1	625..1235	CDD:406268	149/652 (23%)
		PIKKc_SMG1	2113..2418	CDD:270714	174/308 (56%)
		FATC	3623..3652	CDD:396715	21/28 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	328	1.000	Domainoid score	I1177
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	903	1.000	Inparanoid score	I369
OMA	1	1.010	-	-		QHG45627
OrthoDB	1	1.010	-	-		D12810at33208
OrthoFinder	1	1.000	-	-		FOG0007362
OrthoInspector	1	1.000	-	-		oto102961
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6240
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980