DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment xit and Alg6

DIOPT Version :9

Sequence 1:	NP_572355.1	Gene:	xit / 31623	FlyBaseID:	FBgn0029906	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_038966196.1	Gene:	Alg6 / 362547	RGDID:	1308815	Length:	543	Species:	Rattus norvegicus

Alignment Length:	431	Identity:	127/431 - (29%)
Similarity:	193/431 - (44%)	Gaps:	59/431 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 WTLDYPPFFAYFEWLLSQVAKYVDPRMLVV-DNLNYESKATVYFQRLSVIVTD-LVYVLGVRSCL 116
            |.|||||..||...|.:.|||:::|..:.: .:..|||:|...|.|.:|:..| |:|:..|....
  Rat   104 WGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYESQAHKLFMRTTVLAADLLIYIPAVLLYC 168

  Fly   117 GSLGLGRDTQQFFAASMLLLLNVGLIFVDHIHFQYNGLLFGILLLSIGSLIRQRFLWSAFAFAVL 181
            .|| .....::..|:::.:||..|||.:|:.|||||.:..|..|..:..:.....|..:.||.:.
  Rat   169 YSL-KEISPKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSCDWDLLGSLAFCLA 232

  Fly   182 LNFKHIFLYMAPAFGVYLLRFYCLEQASVVSAVGAVVKLLVVGLTPFAVSFGPFW---QQLPQVL 243
            ||:|.:.||.:..|..:||. .|.::..........:::....:..|.:.:.||.   :...||:
  Rat   233 LNYKQMELYHSLPFFCFLLG-KCFKKGLRGKGSALFIRIACTVVASFLLCWLPFLTEREHALQVV 296

  Fly   244 SRLFPFKRGLTHAYWAPNFWALYNAADKLAAGVLKVQDGGASTTSGLVQEVRHSVLPA-ITPPVT 307
            .||||..|||.....| |.|...|.       .||::|                :||. |...::
  Rat   297 RRLFPVDRGLFEDKVA-NIWCSLNV-------FLKIKD----------------ILPRHIQIAIS 337

  Fly   308 FALTALFMLPILVKLFRSAKKQSPLVFLRAVVLCGCSSFVFGWHVHEKAILMVLLPLCL-LTLVN 371
            |..|.|.:||..:||   ..:.|...|...:|.|..|.|:|.:.||||:||:|.||:|| ||.:.
  Rat   338 FCFTFLSLLPACIKL---TVQPSAKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLTEIP 399

  Fly   372 REDARYAYVLGIAGYFSLFPLLFDADLYIPRYSLYMSYVAMMYGQLYRIFPGFRGFHTLEWLYML 436
            .....:..|    ..||:.|||....|.:|.....|:::.    .....||.|.  :|.|....|
  Rat   400 FMSTWFLLV----STFSMLPLLLKDQLLLPSVVTVMAFLI----ACSTFFPMFE--NTSEEQLQL 454

  Fly   437 GFMAIPLYEHLLSFLLHLDQRLPFLP-----LLLTSVYSAL 472
            ...|:.:..||..|        .|||     |.|:||.:.:
  Rat   455 KSFAVSVRRHLPGF--------TFLPRIIQCLFLSSVITMI 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
xit	NP_572355.1	Alg6_Alg8	12..478	CDD:281190	127/431 (29%)
Alg6	XP_038966196.1	Alg6_Alg8	98..521	CDD:397324	127/431 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D379099at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920