DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment xit and gny

DIOPT Version :9

Sequence 1:	NP_572355.1	Gene:	xit / 31623	FlyBaseID:	FBgn0029906	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001260338.1	Gene:	gny / 34409	FlyBaseID:	FBgn0032234	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	143/495 - (28%)
Similarity:	223/495 - (45%)	Gaps:	69/495 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PAYHSTDFEVHRNWLAITHSLPLNQWYVDATSE----WTLDYPPFFAYFEWLLSQVAKYVDPRML 81
            |..|. |:|..|:|..||.:|.:.:||.::::.    |.|||||..||..:|:.::...:|||.:
  Fly    30 PPMHG-DYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTAYHSYLVGRIGASIDPRFV 93

  Fly    82 VV-DNLNYESKATVYFQRLSVIVTD-LVYVLGVRSCLGSLGLG-RDTQQFFAASMLLLLNVGLIF 143
            .: .:..:|||....|.|.:|:..| |:|:..:.....||... |...:.|..: |:....|...
  Fly    94 ELHKSRGFESKEHKRFMRATVVSADVLIYLPAMLLLAYSLDKAFRSDDKLFLFT-LVAAYPGQTL 157

  Fly   144 VDHIHFQYNGLLFGILLLSIGSLIRQRFLWSAFAFAVLLNFKHIFLYMAPAFGVYLLRFYCLEQA 208
            :|:.|||||.:..|...::|.:::|:||..:||.|.:.||:|.:.||.:..|..:||. .|:.|.
  Fly   158 IDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELYHSLPFFAFLLG-ECVSQK 221

  Fly   209 SVVSAVGAVVKLLVVGLTPFAVSFGPFW----QQLPQVLSRLFPFKRGLTHAYWAPNFWALYNAA 269
            |..|.:..:.::..|.|..||:.:.| |    |.:.|||.||||..||:.....| |.|...|..
  Fly   222 SFASFIAEISRIAAVVLGTFAILWVP-WLGSLQAVLQVLHRLFPVARGVFEDKVA-NVWCAVNVV 284

  Fly   270 DKLAAGVLKVQDGGASTTSGLVQEVRHSVLPAITPPVTFALTALFMLPILVKLFRSAKKQSPLVF 334
            .||...:...|                      ...|..|.|.:..||..|.|||   :::.:.|
  Fly   285 WKLKKHISNDQ----------------------MALVCIACTLIASLPTNVLLFR---RRTNVGF 324

  Fly   335 LRAVVLCGCSSFVFGWHVHEKAILMVLLP-LCLLTLVNREDARYAYVLGIAGYFSLFPLLFDADL 398
            |.|:.....:.|:|.:.||||.||:..|| |.||.....|...:..|.    .||:.|||...:|
  Fly   325 LLALFNTSLAFFLFSFQVHEKTILLTALPALFLLKCWPDEMILFLEVT----VFSMLPLLARDEL 385

  Fly   399 YIPRYSLYMSYVAMMYGQLYRIFPGFRGFHTLEWLYMLGFMA-----IPLYEHLLSFLLHLDQRL 458
            .:|.....:::        :.||..|.....|...|.|.::|     :.:...:.|..:....:.
  Fly   386 LVPAVVATVAF--------HLIFKCFDSKSKLSNEYPLKYIANISQILMISVVVASLTVPAPTKY 442

  Fly   459 PFLPLLLTSVYSALGVLYFFGAYYLYALGISWGKVPIASS 498
            |.|..|:.||.|.       |.::|:.|   ||.|...||
  Fly   443 PDLWPLIISVTSC-------GHFFLFFL---WGNVQQFSS 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
xit	NP_572355.1	Alg6_Alg8	12..478	CDD:281190	135/473 (29%)
gny	NP_001260338.1	Alg6_Alg8	30..463	CDD:281190	137/481 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449695
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.741681	Normalized mean entropy	S1324
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D379099at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12413
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.900