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Protein Alignment iav and Trpv1

DIOPT Version :9

Sequence 1:	NP_572353.1	Gene:	iav / 31621	FlyBaseID:	FBgn0086693	Length:	1123	Species:	Drosophila melanogaster
Sequence 2:	NP_114188.1	Gene:	Trpv1 / 83810	RGDID:	628841	Length:	838	Species:	Rattus norvegicus

Alignment Length:	670	Identity:	173/670 - (25%)
Similarity:	268/670 - (40%)	Gaps:	145/670 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 YLGASALHLSIAYSNNELVADLIEAGADIHQRAIGSFFLPRDQQRANPAKSTDYEGLAYMGEYPL 235
            |.|.:|||::|...|..||..|:|.|||:...|.|.||           |.|......|.||.||
  Rat   199 YKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFF-----------KKTKGRPGFYFGELPL 252

  Fly   236 AWAACCANESVYNLLVDCG---SDPDAQDSFGNMILH-MVVVCDK--------LDMFGYAL---- 284
            :.|||....::...|:...   :|..|:||.||.:|| :|.|.|.        ..|:...|
  Rat   253 SLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGA 317

  Fly   285 -RHPKTPAKNGIVNQTGLTPLTLACKLGRAEVFREMLELS---------AREF--WRYSNITCSG 337
             .|| |.....|.|:.|||||.||...|:..|...:|:..         :|:|  |.|..:..|.
  Rat   318 KLHP-TLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSL 381

  Fly   338 YPLNALDTLLPDGRTNWNSALFIIL--NGTKPEHLDMLDGGIIQRLLEEKWKTFAQNQFLKRLLI 400
            |.|:.:||      ...||.|.:|.  :...|...|||....:.|||::||..|.:..|.....:
  Rat   382 YDLSCIDT------CEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFV 440

  Fly   401 LSTHLLCLSVSVYLRPAHDGEAEDEDSEGSDASAAALLDIQSDEGDSGGGDYNAQTVARYCAEFA 465
            ...:::..:.:.|.||.          ||          :...:..:..|||     .|...|..
  Rat   441 YCLYMIIFTAAAYYRPV----------EG----------LPPYKLKNTVGDY-----FRVTGEIL 480

  Fly   466 TLVGVLSYVIFQQGDEIKNQGLSAFLKQLSHAPAKAIFL--FSNLLILACIPFRLIG----DTDT 524
            ::.|.: |..|        :|:..||::  ....|::|:  :|.:|......|.|:.    .:..
  Rat   481 SVSGGV-YFFF--------RGIQYFLQR--RPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQR 534

  Fly   525 EE--AILIFAVPGSWFLLMFFAGAIRLTGPFVTMIYSMITGDMFTFGIIYCIVLCGFSQAFYFLY 587
            :|  |.::|::...|..::::....:..|.:..||..||..|:..|..:|.:.|.|||.|...|.
  Rat   535 KEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLI 599

  Fly   588 -----------------KGHPQVQSTMFNTYTSTWMALFQTTLGDYNYPDLNQTTYPNLSKTVFV 635
                             :|........:|:..||.:.||:.|:|   ..||..|...:. |.||:
  Rat   600 EDGKNNSLPMESTPHKCRGSACKPGNSYNSLYSTCLELFKFTIG---MGDLEFTENYDF-KAVFI 660

  Fly   636 I----FMIFVPILLLNMLIAMMGNTYVTVIEQSEKEWMKQWAKIVVTLERAVPQADAKGYLEAYS 696
            |    ::|...|||||||||:||.|...:.::|:..|..|.|..::..|::..:...|.:.....
  Rat   661 ILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKL 725

  Fly   697 IPLGPSDDSGFEVR---------------GVMVIKS--------KSKTRAKQRKGAVS--NWKRV 736
            :.:|.:.|...:.|               .|.:|..        |.......|.|.||  |||..
  Rat   726 LQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSGRVSGRNWKNF 790

  Fly   737 GRVTL---TALKKRGMTGEE 753
            ..|.|   .:.:.|..|.:|
  Rat   791 ALVPLLRDASTRDRHATQQE 810

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.