| Sequence 1: | NP_572353.1 | Gene: | iav / 31621 | FlyBaseID: | FBgn0086693 | Length: | 1123 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_057197.2 | Gene: | TRPV2 / 51393 | HGNCID: | 18082 | Length: | 764 | Species: | Homo sapiens |
| Alignment Length: | 606 | Identity: | 148/606 - (24%) |
|---|---|---|---|
| Similarity: | 231/606 - (38%) | Gaps: | 150/606 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 157 VFPNLALDVMEG------------EEYLGASALHLSIAYSNNELVADLIEAGADIHQRAIGSFFL 209
Fly 210 PRDQQRANPAKSTDYEGLAYMGEYPLAWAACCANESVYNLLVDCGSDP---DAQDSFGNMILHMV 271
Fly 272 VVCDKLDMFGYAL-------------RHPKTPAKNGIVNQTGLTPLTLACKLGRAEVFREMLELS 323
Fly 324 AREF------------WRYSNITCSGYPLNALDTLLPDGRTNWNSALFIILNGTKPEH---LDML 373
Fly 374 DGGIIQRLLEEKWKTFAQNQFLKRLLILSTHLLCLSVSVYLRPAHDGEAEDEDSEGSDASAAALL 438
Fly 439 DIQSDEGDSG----------GGDYNAQTVARYCAEFATLVGVLSYVIFQQGDEIKNQGLSAFLKQ 493
Fly 494 LSHAPAKAIFLF-------SNLLILACIPFRLIGDTDTEEAILIFAVPGSWFLLMFFAGAIRLTG 551
Fly 552 PFVTMIYSMITGDMFTFGIIYCIVLCGFSQAFYFLYK--GHPQV--------------------Q 594
Fly 595 STMFNTYTSTWMALFQTTLGDYNYPDLNQTTYPNLSKTVFVIFMIFVPILLLNMLIAMMGNTYVT 659
Fly 660 VIEQSEKEWMKQWAKIVVTLE 680 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| iav | NP_572353.1 | ANKYR | <127..>202 | CDD:223738 | 17/56 (30%) |
| ANK repeat | 132..164 | CDD:293786 | 2/6 (33%) | ||
| ANK | 173..315 | CDD:238125 | 51/157 (32%) | ||
| ANK repeat | 173..203 | CDD:293786 | 12/29 (41%) | ||
| Ank_2 | 177..261 | CDD:289560 | 27/86 (31%) | ||
| ANK repeat | 230..261 | CDD:293786 | 11/33 (33%) | ||
| Ank_2 | 235..324 | CDD:289560 | 33/104 (32%) | ||
| ANK | 258..414 | CDD:238125 | 51/183 (28%) | ||
| ANK repeat | 299..329 | CDD:293786 | 15/41 (37%) | ||
| Ion_trans | 501..665 | CDD:278921 | 43/192 (22%) | ||
| TRPV2 | NP_057197.2 | Required for interaction with SLC50A1. /evidence=ECO:0000250 | 1..388 | 81/275 (29%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..46 | ||||
| trp | 27..764 | CDD:273311 | 148/606 (24%) | ||
| ANK repeat | 116..159 | CDD:293786 | 4/23 (17%) | ||
| ANK repeat | 162..193 | CDD:293786 | 12/30 (40%) | ||
| ANK | 163..314 | CDD:238125 | 54/162 (33%) | ||
| ANK repeat | 208..242 | CDD:293786 | 11/33 (33%) | ||
| ANK repeat | 244..278 | CDD:293786 | 7/33 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 562..585 | 1/22 (5%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 725..756 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165145080 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3676 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D386733at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.710 | |||||