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Protein Alignment iav and trpv6

DIOPT Version :9

Sequence 1:	NP_572353.1	Gene:	iav / 31621	FlyBaseID:	FBgn0086693	Length:	1123	Species:	Drosophila melanogaster
Sequence 2:	XP_005173525.1	Gene:	trpv6 / 100000322	ZFINID:	ZDB-GENE-040624-12	Length:	709	Species:	Danio rerio

Alignment Length:	656	Identity:	170/656 - (25%)
Similarity:	289/656 - (44%)	Gaps:	81/656 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 RGALGESLLHVLIICDSKVHTKLARVLLRVFPNLALDVMEGEEYLGASALHLSIAYSNNELVADL 192
            ||.|||:.|||.::.|   :.:.|..|:...|.|..:.|..|.|.|.:|||:::...|..|:.::
Zfish    72 RGELGETALHVAVMND---NFEAAVALMNGAPELINEPMTSELYHGLTALHIAVINQNPNLIWEM 133

  Fly   193 IEAGADI-HQRAIGSFFLPRDQQRANPAKSTDYEGLAYMGEYPLAWAACCANESVYNLLVDCGSD 256
            |:.|||: ..|..|.:|..|            .|||.|.||:.||:|||..|:.:.::|:..|::
Zfish   134 IKRGADVTTPRVTGMYFRKR------------REGLFYYGEHILAFAACVGNKDIMSMLIKAGAN 186

  Fly   257 PDAQDSFGNMILHMVVV-------CDKLD-MFGYALRHPKTPAKNGIVNQTGLTPLTLACKLGRA 313
            ..||||.||.|||::|:       |...| :.............:.:.|..||||..||.:.|..
Zfish   187 IRAQDSRGNTILHLLVLQPNKTTACQIFDFLLAQDAEQDSALPLDMVPNYKGLTPFKLAARDGNV 251

  Fly   314 EVFREMLELSAREFWRYSNITCSGYPLNALDTLLPDGRTNWNSALFIILNGTKPEHLDMLDGGII 378
            .||:.::.......|....::...|.|..:|:     |.:.:|.|.||....|.|...:|:...:
Zfish   252 VVFQHLVNRRKVVQWSLGPVSSYLYDLTEIDS-----RVDEHSVLEIIATSHKKEARRILELTPV 311

  Fly   379 QRLLEEKWKTFAQNQFLKRLLILSTHLLCLSVSVYLRPAHDGEAEDEDSEGSDASAAALLDIQSD 443
            ::|:..||..:.::.|...::|...::...:|....||. .|..|:....|:|.:    :.|:..
Zfish   312 RQLITLKWNLYGKHYFRSLMVIYLVYISIFTVCCINRPL-KGIPENYTKAGNDHT----IKIKKT 371

  Fly   444 EGDSGGGDYNAQT-VARYCAEFATLVGVLSYVIFQ-QGDEIKNQGLSAFLKQLSHAPAKAIFLFS 506
            ..:|    |.:.| ..|..||..:|:|.:..::.: .|  |...|:..|..|.:......:.|.|
Zfish   372 FKES----YQSYTDQLRLIAEIISLIGAIIILLIEIPG--ILAVGVKRFFGQTALGGLFHVTLIS 430

  Fly   507 -NLLILACIPFRLIGDTDTEEAILIFAVPGSWFLLMFFAGAIRLTGPFVTMIYSMITGDMFTFGI 570
             .||:|.....|:.| ...|...:.|::...||.|::||....:.||:|.:|...|.||:..|..
Zfish   431 YALLVLLLCGLRVTG-IQGELIPMAFSLILGWFSLVYFARGFEMLGPYVIVIQKSIFGDITKFMW 494

  Fly   571 IYCIVLCGFSQAFYFLYKGHPQVQSTMFNTYTSTWMALFQTTLGDYNYP-DLNQTTYPNLSKTVF 634
            :..|.|.|.|.|.:..|.....:....:.::..|..:.|:.::|..:.| |....|:|.:..| .
Zfish   495 LSIIFLIGSSAALWIFYMTQEPLALPQYRSFPITLFSQFEVSVGQIDLPVDHTLFTHPVVYWT-H 558

  Fly   635 VIFMIFVPILLLNMLIAMMGNTYVTVIEQSEKEWMKQWAKIVVTLERAVPQA------------- 686
            |.|.:...:||.|:|:|||.:|...|.::.::.|..|.....:.|||.:||.
Zfish   559 VCFSLISNVLLFNLLVAMMSDTQWRVTQERDELWRTQVVATTLMLERKLPQCLWPRLGVCGLMFG 623

  Fly   687 ------------------DAKGYLEAYSIPL-GPSDDSGFEVRGVMVIKSKSKTRAKQRKGAVSN 732
                              ..|.|::|:|..: .|.::...:..|...|...:|.::|:.|   ..
Zfish   624 LGERWYLRVEDRNDIMAQKLKRYVDAFSKDVEAPKEEKPSKSDGEQSIAESNKEKSKKSK---QY 685

  Fly   733 WKRVGR 738
            |..:.|
Zfish   686 WSLIRR 691

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.