Protein Alignment pod1 and Coro1a

DIOPT Version :10

• Sequence 1: NP_001245554.1
• Gene: pod1 / 31620
• FlyBaseID: FBgn0029903
• Length: 1266
• Species: Drosophila melanogaster
• Sequence 2: NP_034028.1
• Gene: Coro1a / 12721
• MGIID: 1345961
• Length: 461
• Species: Mus musculus
• Alignment Length: 439
• Identity: 155/439 - (35%)
• Similarity: 231/439 - (52%)
• Gaps: 39/439 - (8%)

  Fly     6 KASKYKNAAPIVPKAEACVREICVGSYQTYGNNI-AASGAFMAFNWEHT-GSSVAVLPLDDCGRK 68
            ::||:::......||:.|..::.| |..|:.:.. |.:..|||...|.: |.:..||||...||.
Mouse     7 RSSKFRHVFGQPAKADQCYEDVRV-SQTTWDSGFCAVNPKFMALICEASGGGAFLVLPLGKTGRV 70

  Fly    69 SKTMPLLHGHTDTVTDLKFSPFHDGLLATASQDCLVKIWHIPEKGLEQSLSDPEAIFSHKQRRVE 133
            .|.:||:.|||..|.|:.:.|.:|.::|:.|:||.|.:|.||:.||...|.:|........:||.
Mouse    71 DKNVPLVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLVLPLREPVITLEGHTKRVG 135

  Fly   134 TVGFHPTADGLMYSTAAGC---VALFDLSTQKEIFS--NNEHPEVIQSASWREDGSVLATSCKDK 193
            .|.:||||..::.|  |||   :.::|:.|...:.:  .:.||:.|.|..|..||:::.|||:||
Mouse   136 IVAWHPTAQNVLLS--AGCDNVILVWDVGTGAAVLTLGPDVHPDTIYSVDWSRDGALICTSCRDK 198

  Fly   194 NVRIFDPRAAGSPIQLTAESHQSIKDSRVVWLGNQHRILTTGFDAARLRQVIIRDVRNFNTPEKT 258
            .||:.:|| .|:.:......|:..:....|:: ::.:||||||.....|||.:.|.::...|...
Mouse   199 RVRVIEPR-KGTVVAEKDRPHEGTRPVHAVFV-SEGKILTTGFSRMSERQVALWDTKHLEEPLSL 261

  Fly   259 LELDCSTGILMPLFDPDTNMLFLAGKGDTTINYLEITDKDPYL-IEGLRHTGEQTKGACLVPKRA 322
            .|||.|:|:|:|.||||||:::|.||||::|.|.|||.:.|:| ...:..:.|..:|...:|||.
Mouse   262 QELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRG 326

  Fly   323 LKVMEAEVNRVLQLTSNMVIPIMYQVPRKTYRD-FHADLYPETTGYKTELVAGEWLNGSNQA--- 383
            |:|.:.|:.|..:|......||...||||:  | |..||||.|.|....|.|.|||.|.:..
Mouse   327 LEVNKCEIARFYKLHERKCEPIAMTVPRKS--DLFQEDLYPPTAGPDPALTAEEWLGGRDAGPLL 389

  Fly   384 -------VPKMS--------LDPAKREHGDEPIIIHRGN-LSDFVKNLE 416
                   ||..|        ||.|:|....||    .|. .||.|..||
Mouse   390 ISLKDGYVPPKSRELRVNRGLDSARRRATPEP----SGTPSSDTVSRLE 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pod1	NP_001245554.1	DUF1899	3..67	CDD:462645	18/62 (29%)
		WD40	37..>389	CDD:475233	135/378 (36%)
		WD40 repeat	83..127	CDD:293791	15/43 (35%)
		WD40 repeat	132..166	CDD:293791	12/36 (33%)
		WD40 repeat	174..210	CDD:293791	15/35 (43%)
		WD40 repeat	217..260	CDD:293791	12/42 (29%)
		WD40 repeat	267..294	CDD:293791	15/26 (58%)
		WD40	809..>1193	CDD:475233
		WD40 repeat	884..923	CDD:293791
		WD40 repeat	937..973	CDD:293791
		WD40 repeat	979..1016	CDD:293791
		WD40 repeat	1024..1064	CDD:293791
		WD40 repeat	1071..1094	CDD:293791
Coro1a	NP_034028.1	WD40	9..461	CDD:475233	155/437 (35%)
		WD 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	13..63		13/50 (26%)
		WD40 repeat	37..79	CDD:293791	15/41 (37%)
		WD 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	73..110		14/36 (39%)
		WD40 repeat	85..129	CDD:293791	15/43 (35%)
		WD 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	123..160		12/38 (32%)
		WD40 repeat	134..171	CDD:293791	12/38 (32%)
		WD 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	164..204		14/39 (36%)
		WD40 repeat	180..215	CDD:293791	14/35 (40%)
		WD 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	207..251		12/44 (27%)
		WD40 repeat	223..263	CDD:293791	12/40 (30%)
		WD 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	258..296		21/37 (57%)
		WD40 repeat	270..311	CDD:293791	20/40 (50%)
		WD 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221, ECO:0000269|PubMed:16407068	302..349		13/46 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	403..434		10/34 (29%)