Protein Alignment C3G and BUD5

DIOPT Version :9

• Sequence 1: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_009967.2
• Gene: BUD5 / 850405
• SGDID: S000000634
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 415
• Identity: 80/415 - (19%)
• Similarity: 164/415 - (39%)
• Gaps: 122/415 - (29%)

  Fly  1178 YIDALIVHAS-RVQKVA--DNAFCEAFITTFRTFIQPIDVIEKLTHRYTYFFCQVQDNKQKAAKE 1239
            |::.::.|.| :.||.:  |:|   ..:..||.:.....::::|...|...      ||.|....
Yeast   231 YLNKMLPHNSHKWQKPSPFDSA---NLLLNFRDWTTDNALLQELLLSYPTI------NKNKHKNH 286

  Fly  1240 TFALLVRV-------VNDLTSTDLTSQLLSLLVEFV-YQLVCSG--QLYLAKL-----------L 1283
            :...|:::       .::.|..|:.:...|.|.|:. ||.:.:.  ||::.|.           |
Yeast   287 SVPRLIQIWVESYWQDSETTLKDILNFWYSHLAEYYEYQELFADIVQLFINKKRTRQLKIHYIGL 351

  Fly  1284 RNKFVEKVTLYKEPKVYGFV------------GELGGAGSVGGAGIAGSGGCSGTAGGGNQPSLL 1336
            .:|.:|:   .|.|..|..:            .||.||..:           |.......|..||
Yeast   352 TDKEIEE---NKPPLDYENLFLQYEIDKTNANDELCGATDL-----------SDLLFQWKQGELL 402

  Fly  1337 DLKSL-------EIAEQMTLLDAELFTKIEIPEVLLFAKDQCEEKSPNLNKFTEHF--------- 1385
            ::::.       .:|:.:|||::.|:..||..|                  ||.||
Yeast   403 EVEAFALNVSPWSLAKTLTLLESSLYLDIETIE------------------FTRHFKHNDTTIDS 449

  Fly  1386 -----NKMSYWARSKILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALDSGPIRRLEW 1445
                 |::|.:.      |:...::...::.::::......:.|.||..:::::|.:..|.||
Yeast   450 VFTLSNQLSSYV------LETTLQQTHTISYWLQVALSCLYLRNLNSLASIITSLQNHSIERL-- 506

  Fly  1446 QKGITEEVRS------FCALIDSSSSFRAYRQALA---ETNPPCIPYIGLILQDLTFVHVGNQDY 1501
              .:..:|:|      ...::..::::..||:.:.   .:..||:|:..|:::|:||:..||..:
Yeast   507 --SLPIDVKSDHLFQRLKVVVHPNNNYNVYRRTIKHIFHSQLPCVPFTSLLIRDITFIRDGNDTF 569

  Fly  1502 LSKG-VINFSKRWQQYNIIDNMKRF 1525
            ...| .:|.    |::|.|..:..|
Yeast   570 TKDGNNVNM----QKFNQITKIVAF 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571	31/163 (19%)
		RasGEF	1335..1558	CDD:238087	43/222 (19%)
BUD5	NP_009967.2	RasGEFN	230..339	CDD:214571	24/116 (21%)
		RasGEF	409..640	CDD:214539	41/214 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910