Protein Alignment C3G and Rasgrp1

DIOPT Version :9

• Sequence 1: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_038960368.1
• Gene: Rasgrp1 / 29434
• RGDID: 3539
• Length: 818
• Species: Rattus norvegicus
• Alignment Length: 438
• Identity: 93/438 - (21%)
• Similarity: 173/438 - (39%)
• Gaps: 93/438 - (21%)

  Fly  1171 GPEVKGGYIDALIVHASRVQKV-ADNAFC------EAFITTFRTFIQPIDVIEKLTHRYTYFFCQ 1228
            |...||..:|.||  .|.:|.. ||...|      :..:|..|..|...::::||.:.|
  Rat    77 GHLAKGASLDDLI--DSCIQSFDADGNLCRSNQLLQVMLTMHRIIISSAELLQKLMNLY------ 133

  Fly  1229 VQDNKQKAAK--------------ETFALLVRVVNDLTSTDLTSQLLSLLVEFVYQLVCSGQLYL 1279
             :|..:|.:.              ..|.::.::...||||         :.||...:..:|:...
  Rat   134 -KDALEKNSPGICLKICYFVRYWITEFWIMFKMDASLTST---------MEEFQDLVKANGEESH 188

  Fly  1280 AKLL----------RNKFVEKV--TLYKEPKVYGFVGELGGAGSVGGAGIAGSGGCSGTAGGGNQ 1332
            ..|:          ..|..:::  ...|:.||
  Rat   189 CHLIDTTQINSRDWSRKLTQRIKSNTSKKRKV--------------------------------- 220

  Fly  1333 PSLL--DLKSLEIAEQMTLLDAELFTKIEIPEVLLFAKDQCEEKSPNLNKFTEHFNKMSYWARSK 1395
             |||  .|:..|::|.:|.|:.:.|.:|...:...:..:.|.:::|.:.:.....|.:|.|.:..
  Rat   221 -SLLFDHLEPEELSEHLTYLEFKSFRRISFSDYQNYLVNSCVKENPTMERSIALCNGISQWVQLM 284

  Fly  1396 ILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALDSGPIRRL-EWQKGITEEVR----S 1455
            :|.....:.|.:...|||.:.:.|.::.|:|:.:|::..|....|.|| |....:..|:.    .
  Rat   285 VLSRPTPQLRAEVFIKFIHVAQKLHQLQNFNTLMAVIGGLCHSSISRLKETSSHVPHEINKVLGE 349

  Fly  1456 FCALIDSSSSFRAYRQALAETNPPCIPYIGLILQDLTFVHVGNQDYLSKGVINFSKRWQQYNIID 1520
            ...|:.|..::..||:|..|.....||.:|:.|:||..::....|||..|.:|..|....||.|:
  Rat   350 MTELLSSCRNYDNYRRAYGECTHFKIPILGVHLKDLISLYEAMPDYLEDGKVNVQKLLALYNHIN 414

  Fly  1521 NMKRFKKCAYPFRRNERIIRFFDNFKD-FMGEEEMWQISEKIKPRGRR 1567
            .:.:.:..|.|...|:.::.......| :..|:|::::|...:||..|
  Rat   415 ELVQLQDVAPPLDANKDLVHLLTLSLDLYYTEDEIYELSYAREPRNHR 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571	32/167 (19%)
		RasGEF	1335..1558	CDD:238087	56/230 (24%)
Rasgrp1	XP_038960368.1	RasGEFN	77..199	CDD:214571	28/139 (20%)
		RasGEF	224..460	CDD:214539	56/235 (24%)
		EF-hand_7	501..550	CDD:404394
		C1_RASGRP1	563..617	CDD:410410
		cc_RasGRP1_C	760..814	CDD:412086

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810