Protein Alignment C3G and ste6

DIOPT Version :9

• Sequence 1: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_588316.1
• Gene: ste6 / 2538724
• PomBaseID: SPCC1442.01
• Length: 911
• Species: Schizosaccharomyces pombe
• Alignment Length: 455
• Identity: 104/455 - (22%)
• Similarity: 182/455 - (40%)
• Gaps: 102/455 - (22%)

  Fly  1166 KREEDGPEVKGGYIDALIVHASRVQKVADNAFCEAFITTFRTFIQPIDVIEKLTHRYTYFFCQVQ 1230
            |.|:|| ::|...:..:|.:..|.. :....|...|:.|:.:.|...|:...|...:. |.|.:.
pombe   486 KIEQDG-KIKTATLVFIINYLLRTD-IDSTFFTTIFLNTYASMISSSDLFSILGAHFR-FICSLN 547

  Fly  1231 DNKQKAAKETF----------------ALLVRVVNDLTSTDLTSQLLSLLVEFVYQLVCSGQLYL 1279
            ..|.......|                :.||..:::..|.....::..:...||.....|.:..|
pombe   548 FGKISFISHEFYRVSKRFLDILLIWFESYLVEELDNSKSIFFLFKIYKVFEVFVVPHFASAEELL 612

  Fly  1280 ---------------AKLLRNK----FVEKVTLYKEPKVYGFVGELGGAGSVGGAGIAGSGGCSG 1325
                           .|:|..|    .:|.::|:..|....:..||
pombe   613 HSLSHLLHHPSTKRSHKMLEGKELSQELEDLSLHNSPDPIIYKDEL------------------- 658

  Fly  1326 TAGGGNQPSLLDLKSLEIAEQMTLLDAELFTKIEIPEVLLFAKDQCEEKSPNLNKF-----TEHF 1385
                     :|.|...|||:|:.:|:.:.|:.|...:.|....|       |||:|     |..|
pombe   659 ---------VLLLPPREIAKQLCILEFQSFSHISRIQFLTKIWD-------NLNRFSPKEKTSTF 707

  Fly  1386 ---NKMSYWARSKILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALDSGPIRRLE--W 1445
               |.:..:....|::.::.:.|...:..||::..:||::||:.|..:::|||:|.||.||.  |
pombe   708 YLSNHLVNFVTETIVQEEEPRRRTNVLAYFIQVCDYLRELNNFASLFSIISALNSSPIHRLRKTW 772

  Fly  1446 QKGITEEVRSF---CALIDSSSSFRAYRQALAETNPPCIPYIGLILQDLTFVHVGNQDYLSKGVI 1507
            ....::.:.||   ..|.::..:|..||..|.....||:|::|:...||||:..||:|.. :.:|
pombe   773 ANLNSKTLASFELLNNLTEARKNFSNYRDCLENCVLPCVPFLGVYFTDLTFLKTGNKDNF-QNMI 836

  Fly  1508 NFSKRWQQYNIIDNMKRFKKCAYPFR--------RNERIIRFFDNFKDFMGEEEMWQISEKIKPR 1564
            ||.||.:...|::.:|:|:...|.|.        .||.|.|       ......::|.|..::||
pombe   837 NFDKRTKVTRILNEIKKFQSVGYMFNPINEVQELLNEVISR-------ERNTNNIYQRSLTVEPR 894

  Fly  1565  1564
            pombe   895  894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571	28/170 (16%)
		RasGEF	1335..1558	CDD:238087	69/243 (28%)
ste6	NP_588316.1	SH3	7..55	CDD:214620
		RasGEFN	489..604	CDD:214571	20/117 (17%)
		RasGEF	659..895	CDD:214539	72/251 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23113
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2063
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940