DRSC/TRiP Functional Genomics Resources

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Protein Alignment C3G and Rasgrp1

DIOPT Version :10

Sequence 1:NP_572350.2 Gene:C3G / 31618 FlyBaseID:FBgn0259228 Length:1571 Species:Drosophila melanogaster
Sequence 2:NP_035376.1 Gene:Rasgrp1 / 19419 MGIID:1314635 Length:795 Species:Mus musculus


Alignment Length:74 Identity:16/74 - (21%)
Similarity:31/74 - (41%) Gaps:10/74 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 DNVYGAWSMRRMFIAFSTKFFYPL-----CMTAKTASLYIMVVITVERWIAVCRPLQVHIWCTFK 132
            ||.:|    :|:....:...|..|     |:..:..:|..::...:.|..|...|..|: |.|..
Mouse   884 DNTFG----QRLLYLCTQGLFECLALNLYCLRGEQRALTTVINHRIRRMSAEVNPSLVN-WLTSM 943

  Fly   133 NSVRIVIAI 141
            .|:|:.:.:
Mouse   944 MSMRLHVIL 952

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
C3GNP_572350.2 RasGEFN 1170..1306 CDD:214571
RasGEF 1335..1558 CDD:238087
Rasgrp1NP_035376.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
RasGEFN 54..176 CDD:214571
Ras exchanger motif region, required for transforming activity 57..110
RasGEF 201..437 CDD:214539
FRQ1 <471..527 CDD:444056
C1_RASGRP1 540..594 CDD:410410
Suppress the PT region-mediated translocation to plasma membrane 686..694
PT region, mediates the BCR-dependent translocation to plasma membrane 717..795
cc_RasGRP1_C 737..791 CDD:412086
Blue background indicates that the domain is not in the aligned region.

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