Protein Alignment C3G and Rasgrp2

DIOPT Version :9

• Sequence 1: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_035372.2
• Gene: Rasgrp2 / 19395
• MGIID: 1333849
• Length: 608
• Species: Mus musculus
• Alignment Length: 410
• Identity: 90/410 - (21%)
• Similarity: 161/410 - (39%)
• Gaps: 83/410 - (20%)

  Fly  1191 KVADNAFCEAFITTFRTFIQPIDVIEKLTHRYTYFFCQVQDNKQKAAKETFALLVRVVNDLTST- 1254
            ||.|......|:.....:|....:..||.|.|..   ..:||......:|..|:...::...:.
Mouse    29 KVRDPQLVRMFLMMHPWYIPSSQLASKLLHFYQQ---SRKDNSNSLQMKTCHLVRYWISAFPAEF 90

  Fly  1255 DLTSQLLSLLVEFVYQLVCSGQLYLAKLLRNKFVEKVTLYK-----------EPKVYGFVGELGG 1308
            ||..:|...:.|....|...|....:.|:.   :|.|..||           |.|
Mouse    91 DLNPELAEQIKELKALLDQEGNRRHSSLID---IESVPTYKWKRQVTQRNPVEQK---------- 142

  Fly  1309 AGSVGGAGIAGSGGCSGTAGGGNQPSLL--DLKSLEIAEQMTLLDAELFTKIEIPEVLLFAKDQC 1371
                                 ..:.|||  .|:.:|:||.:|.|:...|.||...:...|....|
Mouse   143 ---------------------KRKMSLLFDHLEPMELAEHLTYLEYRSFCKILFQDYHSFVTHGC 186

  Fly  1372 EEKSPNLNKFTEHFNKMSYWARSKILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALD 1436
            ...:|.|.:|...||.:|.|.:..||....|.:|...:..|:.:.:.|.::.|:|:.:|::..|.
Mouse   187 TVDNPVLERFISLFNSVSQWVQLMILSKPTATQRALVITHFVHVAERLLQLQNFNTLMAVVGGLS 251

  Fly  1437 SGPIRRLE-------------WQKGITEEVRSFCALIDSSSSFRAYRQALAETNPPCI----PYI 1484
            ...|.||:             |: |:||       |:.::.::..||:.||    .|:    |.:
Mouse   252 HSSISRLKETHSHVSPDTIKLWE-GLTE-------LVTATGNYSNYRRRLA----ACVGFRFPIL 304

  Fly  1485 GLILQDLTFVHVGNQDYLSKG--VINFSKRWQQYNIIDNMKRFKKCAYPFRRNERIIRFFD-NFK 1546
            |:.|:||..:.:...|:|..|  .:|.:|..|.:.|::.:........|.:.|..::.... :..
Mouse   305 GVHLKDLVALQLALPDWLDPGRTRLNGAKMRQLFCILEELAMVTSLRPPVQANPDLLSLLTVSLD 369

  Fly  1547 DFMGEEEMWQISEKIKPRGR 1566
            .:..|:|::|:|.:.:||.:
Mouse   370 QYQTEDELYQLSLQREPRSK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571	26/126 (21%)
		RasGEF	1335..1558	CDD:238087	60/244 (25%)
Rasgrp2	NP_035372.2	RasGEFN	7..121	CDD:214571	20/97 (21%)
		RasGEF	150..387	CDD:214539	59/248 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..405		2/8 (25%)
		EFh	430..481	CDD:238008
		C1	499..548	CDD:237996
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	555..596

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810