Protein Alignment C3G and Sos

DIOPT Version :10

• Sequence 1: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_061509646.1
• Gene: Sos / 1280136
• VectorBaseID: AGAMI1_004113
• Length: 1886
• Species: Anopheles gambiae
• Alignment Length: 893
• Identity: 185/893 - (20%)
• Similarity: 337/893 - (37%)
• Gaps: 244/893 - (27%)

  Fly   795 TTTGYGSSEVEQLQQQQQQQTTTTPADLAPALPPKSIQRSSLTRHDSPGVGDELDEVQSSSGWAS 859
            :.|..||  :|.:.:..|:||                         .|.:|...:|:..::.:..
Mosquito   262 SVTLLGS--LEDVIEMSQEQT-------------------------PPCIGSCFEELAEAAEFDV 299

  Fly   860 HRSSQSEVAELRQLSPLHHLNHHPHTASAGQLQQWHSKHHSLIEG-----PRLQLAGSGSCSAFD 919
            :.....::..:.....|.:|...|..||:     ..|..|...|.     |:|.|...|..
Mosquito   300 YAKYAKDITSVTAKEALANLLARPEVASS-----LMSAGHGFKEAVKFYLPKLLLGPIGHA---- 355

  Fly   920 QRHLDQEPPPLPIKKKHILAYMEICSASTRSIEQHRHTMHACNISRNISHSQTMNIMPMSKELSP 984
            |.:||.      ||   :|..:........|.||                     :..:.|.|..
Mosquito   356 QLYLDY------IK---VLLQLSPSQEDKESFEQ---------------------VQGLLKPLQC 390

  Fly   985 ELEMPPALPPKNY------KQRKATSMVASPTLQPVIVTTPPPSPKPTLGENGSTGRPDSRMATV 1043
            ||:...:|.||.|      :.|:.:::..:..||..:             |:.     |..:...
Mosquito   391 ELQSISSLLPKEYFTRVNSRARRQSAIEKTRDLQNTV-------------EHW-----DKDVGQC 437

  Fly  1044 CEELNDAVASEDAMPEPRSPVLDSNENVSAVDDGQTFYCHSHQ--LPAAE----------MEMSE 1096
            |.|.    ..||.:.:..|....:...| .:.||....|.:.:  :|...          |...|
Mosquito   438 CNEF----IREDTLAKLSSGKRQTERKV-FLFDGLLVLCKARRQIVPGNNYDYRQKERFFMRKVE 497

  Fly  1097 DASSADNQPITTPQVLEEQEEPTAESRPLVAVHESVKPANVDEDEEAERADMLI----NMLEEV- 1156
            .....|     |.::....|....|.:.:|.:.::.:..|      ...||:::    :|||.:
Mosquito   498 IIDRPD-----TDELKHAFEISPREQQSVVLITKNAQHKN------DWMADLIMLNTKSMLERIL 551

  Fly  1157 ------------------NITRY--------LILKKREEDG-PEVKGG----YIDALIVHASRVQ 1190
                              ::.::        ::|::||..| |.:||.    .|:.|..|.
Mosquito   552 DSILLDIEKKHPLRLPSPDMYKFAVPDGPSNIVLEEREGTGVPLIKGATLCKLIERLTYHI---- 612

  Fly  1191 KVADNAFCEAFITTFRTFIQPIDVIEKLTHRYTY---------------------FFCQVQDNKQ 1234
             .||..|...|:||:|:|..|.::::.|..|:..                     |....|....
Mosquito   613 -YADPMFVRTFLTTYRSFCSPKELLQLLVERFDIPDPAVVYDPAAEKELAGDTDKFHKNSQREDW 676

  Fly  1235 KAAKETFALLV--RVVNDLT--------STDLTSQLLSLLVEFVYQLVCSGQLYLAKLLRNKFVE 1289
            |..|:.:...|  ||:|.|.        ..:...:||..|..|:       :....|.:| |:|:
Mosquito   677 KRYKKEYVQPVQFRVLNVLRHWVDHHFYDFERDGELLESLERFL-------ETVRGKSMR-KWVD 733

  Fly  1290 KVTLYKEPKVYGFVGELGGAGSVGGAGIAGSGGCSGTA-------GGGNQPSLLDLKSLEIAEQM 1347
            .|....:.|         .........|..:.|.|..|       .|.|:.:||.|..||:|.|:
Mosquito   734 SVMKIVQRK---------NESEDNHRQITFAFGHSPPAIEHHLPLNGENEFNLLMLHPLELARQL 789

  Fly  1348 TLLDAELFTKIEIPEV---LLFAKDQCEEKSPNLNKFTEHFNKMSYWARSKILRLQDAKEREKHV 1409
            |||:.|::..::..|:   :...||: |..||||.|...|....:.|....|:..::.:||....
Mosquito   790 TLLEFEMYKNVKPSELVGSVWTGKDK-ETTSPNLLKIMHHTTNFTRWIEKSIIEAENFEERVAMA 853

  Fly  1410 NKFIKIMKHLRKMNNYNSYLALLSALDSGPIRRLEWQKGIT--------EEVRSFCALIDSSSSF 1466
            ::.|::|..|:.:||:|..|:::||.....:.||:    :|        ::|.:.|..: ::|.|
Mosquito   854 SRAIEVMMVLQDLNNFNGVLSIVSAFQGAAVHRLK----LTLEDIPKRHQQVLAECREL-NNSHF 913

  Fly  1467 RAYRQALAETNPPCIPYIGLILQDLTFVHVGNQDYL-SKGVINFSKRWQQYNIIDNMKRFKKCAY 1530
            :.|::.|...||||:|:.|:.|.::..:..||.|:| :..:||||||.:...|...:::::...|
Mosquito   914 KKYQEKLRSINPPCVPFFGMYLTNILHIEEGNPDFLPNTELINFSKRRRVAEITGEIQQYQNQPY 978

  Fly  1531 PFRRNERIIRFFDNFKDFMG------EEEMWQISEKIKPRG-RRPVNY 1571
            ..:.:..|..|.:|...|.|      :..:::.|::|:|:. |:|:.:
Mosquito   979 CLKVDPSIRNFLENLDPFKGMSITEIQNYLYEESKRIEPKNCRQPLKF 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571	37/171 (22%)
		RasGEF	1335..1558	CDD:238087	67/240 (28%)
Sos	XP_061509646.1	None