DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment shf and Ten-m

DIOPT Version :9

Sequence 1:NP_001284963.1 Gene:shf / 31617 FlyBaseID:FBgn0003390 Length:460 Species:Drosophila melanogaster
Sequence 2:NP_001262211.1 Gene:Ten-m / 40464 FlyBaseID:FBgn0004449 Length:3349 Species:Drosophila melanogaster


Alignment Length:365 Identity:82/365 - (22%)
Similarity:125/365 - (34%) Gaps:96/365 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 RVTNDLRDTTLYNFLVIPSEVNYVNFTWK---------SGRRKYF-----YDFDRLQ---TMDES 196
            ::|.:::..:.:|.....||..||.|.:.         .|||...     |.|..:.   :....
  Fly   957 KLTKEIQPYSYWNMQFYQSEPAYVKFDYTIPRGASIGVYGRRNALPTHTQYHFKEVLSGFSASTR 1021

  Fly   197 ILKAPTLSIRKSGRIPQEQKNFSIFL----------------------PCTGNSSGTASFNVGLK 239
            ..:|..|||.:......|..::.:.|                      .|....||.....:|  
  Fly  1022 TARAAHLSITREVTRYMEPGHWFVSLYNDDGDVQELTFYAAVAEDMTQNCPNGCSGNGQCLLG-- 1084

  Fly   240 IQTRHNKPLSG-------TPIRLNFKKECAHRGVYDIDASNPTSLTTLQAPDPECSLK------- 290
             ..:.|....|       .|:.      |:..|.|    :|...:........||||:       
  Fly  1085 -HCQCNPGFGGDDCSESVCPVL------CSQHGEY----TNGECICNPGWKGKECSLRHDECEVA 1138

  Fly   291 -CGKNGYCNEHHICKCNVGYTGQYCETAFC-FPQCLNGGNCTAPSVCTCPEGYQGTQC-----EG 348
             |..:|:|.... |:|..||.|::||...| .|.|...|.| |...|.|.:|::|..|     :.
  Fly  1139 DCSGHGHCVSGK-CQCMRGYKGKFCEEVDCPHPNCSGHGFC-ADGTCICKKGWKGPDCATMDQDA 1201

  Fly   349 GICKDKCLNGGKC-IQKDKCQCSKGYYGLRCEYSKCVIPCKNEGRCIGNNLCRCPNGLRGDHCEI 412
            ..|...|...|.. :....|.|...:.|..|....|.:.|...|||.| :.|.|.....|::|  
  Fly  1202 LQCLPDCSGHGTFDLDTQTCTCEAKWSGDDCSKELCDLDCGQHGRCEG-DACACDPEWGGEYC-- 1263

  Fly   413 GRKQRSIC--------KCRNGTCVSHKHCKCHPGFYGRHC 444
               ...:|        :|:||||:      |..|:.|:||
  Fly  1264 ---NTRLCDVRCNEHGQCKNGTCL------CVTGWNGKHC 1294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shfNP_001284963.1 WIF 137..258 CDD:280237 25/154 (16%)
Ten-mNP_001262211.1 TNFRSF 1069..1198 CDD:304602 36/143 (25%)
CRD2 1106..1151 CDD:276900 11/49 (22%)
EGF_2 1139..1162 CDD:285248 8/23 (35%)
Keratin_B2 1162..1330 CDD:279797 41/146 (28%)
EGF_2 1167..1194 CDD:285248 10/27 (37%)
DUF3844 1171..>1235 CDD:289707 16/64 (25%)
EGF_2 <1272..1294 CDD:285248 8/27 (30%)
NHL 1750..2065 CDD:302697
NHL repeat 1784..1830 CDD:271320
NHL repeat 1854..1888 CDD:271320
NHL repeat 1911..1950 CDD:271320
NHL repeat 1972..2005 CDD:271320
NHL repeat 2039..2065 CDD:271320
RHS_repeat 2183..2218 CDD:283287
RhsA 2347..3020 CDD:225750
YD_repeat_2x 2795..2836 CDD:273728
Rhs_assc_core 2905..2980 CDD:274730
Tox-GHH 3193..3268 CDD:292269
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1225
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.