DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment shf and Tenm2

DIOPT Version :9

Sequence 1:NP_001284963.1 Gene:shf / 31617 FlyBaseID:FBgn0003390 Length:460 Species:Drosophila melanogaster
Sequence 2:XP_006533350.1 Gene:Tenm2 / 23964 MGIID:1345184 Length:2774 Species:Mus musculus


Alignment Length:396 Identity:93/396 - (23%)
Similarity:138/396 - (34%) Gaps:146/396 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 RVTNDLRDTTLYNFLVIPSEVNYVNFTWKSGRRKYF--------------YDF-DRLQTMDE-SI 197
            |||.::.....:...:..|:..::.|....|:...|              ||| :||...:: |:
Mouse   456 RVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDGKEKWSV 520

  Fly   198 LKAPTLSIRKSGRIPQEQKNFSIFLPCTGNSSGTASFNVGLKIQTRHNKPLSGTPIRLNFKKECA 262
            :::|    |:...|....:|.::|:         ...:|||                       .
Mouse   521 VESP----RERRSIQTLVQNEAVFV---------QYLDVGL-----------------------W 549

  Fly   263 HRGVY------DIDASNPTSLTTLQAPDPECSLKCGKNGYCNEHHICKCNVGYTGQYCETAFCFP 321
            |...|      ::.:.|...|.::|    :|...|..||.| ...:|.|..|:.|..|..|.| |
Mouse   550 HLAFYNDGKDKEMVSFNTVVLDSVQ----DCPRNCHGNGEC-VSGLCHCFPGFLGADCAKAAC-P 608

  Fly   322 --------------QCLNG----------GNCTAPSV----------CTCPEGYQGTQCEGGICK 352
                          ||.:|          ..|..||.          |.|..||:|..||...|.
Mouse   609 VLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCAAGYKGEHCEEVDCL 673

  Fly   353 D-KCLNGGKCIQKDKCQCSKGYYGLRCEYSK---------------------------------- 382
            | .|.:.|.|: ..:|.||.|:.||.||.::                                  
Mouse   674 DPTCSSHGVCV-NGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDSGLCSCDPNWMGPDCSVE 737

  Fly   383 -CVIPCKNEGRCIGNNLCRCPNGLRGDHCEIGRKQRSIC--KC-RNGTCVSHKHCKCHPGFYGRH 443
             |.:.|...|.||| ..|||..|..|..|:    || :|  :| .:|||...| |:|..|:.|.|
Mouse   738 VCSVDCGTHGVCIG-GACRCEEGWTGAACD----QR-VCHPRCIEHGTCKDGK-CECREGWNGEH 795

  Fly   444 CN-GRK 448
            |. ||:
Mouse   796 CTIGRQ 801

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shfNP_001284963.1 WIF 137..258 CDD:280237 21/124 (17%)
Tenm2XP_006533350.1 Ten_N 10..374 CDD:399476
exchanger_TraA <570..885 CDD:411343 69/246 (28%)
NHL 1240..1570 CDD:302697
NHL repeat 1240..1279 CDD:271320
NHL repeat 1291..1334 CDD:271320
NHL repeat 1358..1396 CDD:271320
NHL repeat 1412..1453 CDD:271320
NHL repeat 1476..1509 CDD:271320
NHL <1543..>1634 CDD:302697
NHL repeat 1544..1570 CDD:271320
NHL repeat 1546..1584 CDD:271320
RhsA 1689..2482 CDD:225750
Rhs_assc_core 2391..2468 CDD:274730
Tox-GHH 2690..2767 CDD:406145
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1225
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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