Protein Alignment shf and T01D3.1

DIOPT Version :9

• Sequence 1: NP_001284963.1
• Gene: shf / 31617
• FlyBaseID: FBgn0003390
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001256538.1
• Gene: T01D3.1 / 179859
• WormBaseID: WBGene00011326
• Length: 3226
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 118/522 - (22%)
• Similarity: 182/522 - (34%)
• Gaps: 160/522 - (30%)

  Fly    55 HG-----NTSDGLD--NFADQDASFVGHGHQPRRG----QRKKQQGGGGGG-------------- 94
            ||     |::|.:|  |...::|:....|...||.    :..|.|.|.|.|
 Worm   770 HGIEITQNSNDVVDLGNVIIEEANESAIGVDERRDDLLIKNVKIQNGAGSGIDFMTPTGNIELQN 834

  Fly    95 -----SGGGG--------------------------GNGG---GGG-----SRHN-RNEESGISL 119
                 .||.|                          |:.|   .||     ..|| :.:::.:|
 Worm   835 IEVKNMGGYGIHISEFPSSPLHAVLLDNVSVIEQKRGHAGILISGGWIQNVGMHNLKFKDNAVS- 898

  Fly   120 WINEQQLKMLTALYFPQGYSERLYAIHNSRVTNDLRDTTLYNFLVIPSEVNYVNFTWKSGRRKYF 184
                   .::.||....| :|:|..:.||...   |:|.:...:.:.|   ..|...:..|
 Worm   899 -------SLIVALECNDG-NEKLIKMENSTFE---RNTDIVQHIQLGS---CANLQMEKNR---- 945

  Fly   185 YDFDRLQTMDES-ILKAPTLSIRKSGRIPQEQKNFS----IFLPCT---------------GNSS 229
            ||.:.:..:..: ::.:.....:|:|.:...:.||:    |:....               ||.:
 Worm   946 YDSNNIDGIGSTLVITSENNEKKKNGVMEIVKNNFTNNGGIYTVTVDTNLHDAYFTDNNLKGNEN 1010

  Fly   230 GTASFNV---GLKIQTRH--NK------------PLSGTPIRLNFKKECAHRGVYD--------- 268
            ..|...:   .:||.|.:  ||            |:..|....|...|.|.....|
 Worm  1011 SGAVLKISGENVKIVTNNFDNKDSKYQIGYSDDSPIDATFNEWNGLDEDAVLKTIDAKEGSVLVV 1075

  Fly   269 ------------IDASNPTSLTTLQAPDPECSLKCGKNGYCNEHHICK-----CNVGYTGQYCE- 315
                        |||.  |::..:..|| ..::||....||:....||     |..||||..|.
 Worm  1076 PYGSSTITTDNQIDAL--TTVVPVTVPD-SLNIKCAHLAYCSRRGTCKEGICICPHGYTGFDCSI 1137

  Fly   316 TAFCFPQCLNGGNCTAPSVCTCPEGYQGTQCEGGICKDKCLNGGKCIQKDKCQCSKGYYGLRCEY 380
            ..||  .|...|.|...::|.|.:|:.|:.|....|...|...|||||.:.|:|..|:.|..|..
 Worm  1138 PLFC--NCSGNGLCNLLNICLCNDGWSGSDCSIPRCLTNCTGHGKCIQPNSCECDAGWMGETCSV 1200

  Fly   381 SKCVIPCKNEGRCIGNNLCRCPNGLRGDHCEIGRKQRSIC-KCR-NGTCVSHKHCKCHPGFYGRH 443
            :.|:......|.|..|.||:|.:|.:|..|:|     .:| .|. ||.|.....|.|...:.|..
 Worm  1201 TSCIDSQCTHGHCGTNGLCKCEDGWQGSRCQI-----PLCNSCSLNGICTRPGFCSCFEDYGGSD 1260

  Fly   444 CN 445
            |:
 Worm  1261 CS 1262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shf	NP_001284963.1	WIF	137..258	CDD:280237	28/157 (18%)
T01D3.1	NP_001256538.1	Beta_helix	276..417	CDD:289971
		Beta_helix	392..544	CDD:289971
		Beta_helix	<739..848	CDD:289971	18/77 (23%)
		Beta_helix	819..1004	CDD:289971	30/203 (15%)
		EGF_2	<1143..1166	CDD:285248	7/22 (32%)
		EGF_2	<1175..1198	CDD:285248	10/22 (45%)
		DSL	<1188..1230	CDD:302925	13/41 (32%)
		EGF_2	1269..1299	CDD:285248
		Cadherin_repeat	2692..2776	CDD:206637
		DUF4758	2952..3130	CDD:292572

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910