DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shf and tnca

DIOPT Version :9

Sequence 1:	NP_001284963.1	Gene:	shf / 31617	FlyBaseID:	FBgn0003390	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	XP_021332057.1	Gene:	tnca / 100149028	ZFINID:	ZDB-GENE-130530-849	Length:	2336	Species:	Danio rerio

Alignment Length:	191	Identity:	58/191 - (30%)
Similarity:	79/191 - (41%)	Gaps:	34/191 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 CSLKCGKNGYCNEHHICKCNVGYTGQYCETAFCFPQCLNGGNCTAPSVCTCPEGYQGTQCEGGIC 351
            |...|...|:|.:.. |.|:.||||:.|.:..|...|.:.|.| :..||.|..|:.|..|....|
Zfish   315 CPNDCSGRGFCIDGR-CVCDAGYTGEDCSSLTCPNNCNDRGRC-SNGVCICEVGFHGEDCGRISC 377

  Fly   352 KDKCLNGGKCIQKDKCQCSKGYYGLRCEYSKCVIPCKNEGRCIGNNLCRCPNGLRGDHCEI---- 412
            ...|.|.|.|:. .:|:|..|:.|..|....|...|.|.|||: |..|.|..|...:.|.:
Zfish   378 PSNCNNRGHCVD-GRCECDVGFQGHDCSELSCPNNCNNRGRCV-NGQCVCDEGFGSEDCGLKTCP 440

  Fly   413 ----GRKQ----RSIC----------------KCRN-GTCVSHKHCKCHPGFYGRHCNGRK 448
                ||.|    ..:|                .|:| |.|::.: |.|..||.|..|:.||
Zfish   441 SDCYGRGQCVDGECVCFANFAGEDCSELRCPNSCQNRGRCIAGQ-CVCDEGFTGEDCSQRK 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shf	NP_001284963.1	WIF	137..258	CDD:280237
tnca	XP_021332057.1	EGF_2	189..217	CDD:285248
		EGF_2	316..341	CDD:285248	9/25 (36%)
		EGF_2	377..403	CDD:285248	9/26 (35%)
		EGF_2	408..434	CDD:285248	10/26 (38%)
		EGF_2	470..496	CDD:285248	9/26 (35%)
		EGF_2	496..527	CDD:285248	3/5 (60%)
		EGF_2	530..558	CDD:285248
		FN3	593..679	CDD:238020
		fn3	682..763	CDD:306538
		fn3	772..852	CDD:306538
		FN3	862..947	CDD:238020
		FN3	954..1036	CDD:238020
		FN3	1087..1171	CDD:238020
		fn3	1210..1289	CDD:306538
		fn3	1301..1376	CDD:306538
		fn3	1392..1464	CDD:306538
		FN3	1486..1570	CDD:238020
		fn3	1574..1649	CDD:306538
		fn3	1665..1740	CDD:306538
		fn3	1756..1829	CDD:306538
		fn3	1846..1925	CDD:306538
		fn3	1935..2013	CDD:306538
		fn3	2023..2096	CDD:306538
		FReD	2114..2323	CDD:238040
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1225
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810