DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shf and tnr

DIOPT Version :9

Sequence 1:	NP_001284963.1	Gene:	shf / 31617	FlyBaseID:	FBgn0003390	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001107287.1	Gene:	tnr / 100135076	XenbaseID:	XB-GENE-948286	Length:	1350	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	79/320 - (24%)
Similarity:	113/320 - (35%)	Gaps:	93/320 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 RLQTMDESILKAPTLSIR--KSGRIPQ---EQK----------NFSIFL--PC------------ 224
            |.|...|...:.|.|.|:  |.|.:..   |.|          ||::.|  ||
Frog    28 RSQCQSELTGQTPRLDIQVDKGGNMTDHGIENKQNPMVFNHVYNFNVPLSFPCTLEPETPEDGSW 92

  Fly   225 -TGNSSGTASFNVGLKIQTRHNKPLSGTPIRL-------------------------NFKKECAH 263
             |..:..||  :.|.:|...|:   ...|.||                         ..::.|..
Frog    93 VTQQTENTA--DAGSQITFTHS---IRVPQRLCQCYTTPHAVQHLLSRIEALEREVMLLRERCND 152

  Fly   264 RGVYDIDASNPTSLTTLQAPDPECSLKCGKNGYCNEHHICKCNVGYTGQYCETAFCFPQCLNGGN 328
            |...|.:|:..|...      |.||   |...:..:.  |.||.|:.|:.|....|..:|...|.
Frog   153 RACQDAEATGLTEFA------PPCS---GHGNFTVDS--CICNQGWGGENCSEPLCPLECSGRGT 206

  Fly   329 CTAPSVCTCPEGYQGTQCEGGICKDKCLNGGKCIQKDKCQCSKGYYGLRCEYSKCVIPCKNEGRC 393
            | ...:|.|...|.|..|...:|.::|...|.| |..:|.|...|.|:.|...:|...|..:|||
Frog   207 C-IEGMCVCEPDYTGEWCTDLLCPEECSPHGLC-QDGQCVCQDPYIGIGCTELRCPGDCLGKGRC 269

  Fly   394 IGNNLCRCPNGLRGDHCE--------IGRKQRSICKCRNGTCVSHKHCKCHPGFYGRHCN 445
             .|..|.|.:|..|:.|.        .||.|     |::|.      |:|..|:.|:.|:
Frog   270 -ANGTCVCQDGYAGEDCGRMWCINACSGRGQ-----CQDGV------CECEEGYSGQDCS 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shf	NP_001284963.1	WIF	137..258	CDD:280237	24/123 (20%)
tnr	NP_001107287.1	EGF_alliinase	153..196	CDD:282688	14/53 (26%)
		EGF_2	198..223	CDD:285248	7/25 (28%)
		EGF_2	260..285	CDD:285248	9/25 (36%)
		EGF_2	292..316	CDD:285248	9/34 (26%)
		FN3	321..410	CDD:238020
		fn3	413..493	CDD:278470
		fn3	502..582	CDD:278470
		FN3	592..676	CDD:238020
		fn3	684..763	CDD:278470
		fn3	773..840	CDD:278470
		fn3	862..939	CDD:278470
		fn3	949..1018	CDD:278470
		FN3	1037..1122	CDD:238020
		FReD	1129..1337	CDD:238040
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910