DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14439 and CIN10

DIOPT Version :9

Sequence 1:	NP_001188550.1	Gene:	CG14439 / 31614	FlyBaseID:	FBgn0029898	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_010675.3	Gene:	CIN10 / 851995	SGDID:	S000002795	Length:	555	Species:	Saccharomyces cerevisiae

Alignment Length:	474	Identity:	96/474 - (20%)
Similarity:	157/474 - (33%)	Gaps:	142/474 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 TIAGVFMGF-----AADKYNRVNMLTVCTVIFGIAMILQGTVKEYWQLVILRMI--MAAGESG-C 168
            |..|.|.|.     .||:|.|...|.:|..||.:|.|.....:....|:..|::  :|.|.|. |
Yeast    89 TSVGSFFGSILAFPLADRYGRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQC 153

  Fly   169 NPLATGIMSDIFPEDKRALVMAIFNWGIYGG----YGI------------------AFPVGRYIT 211
            .||   .:|:|.|...|..::.:....|.||    |.|                  |.|...:::
Yeast   154 VPL---FLSEISPSRIRGFMLTLNIIAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLS 215

  Fly   212 KLNF------WNL----------GWRVCYLGAGVLTV---------------------------- 232
            .|:|      |::          ..|:.|..|....|
Yeast   216 ILDFIPESPRWSISKGDILYTRDSLRMLYPTASTYHVNSKIKQLIIELDKLRLYEDASEPLLVQS 280

  Fly   233 -----IMAALTGTTLREPERKAIGEGDRQTSS--GKPVSLWQVIKNPA--------------MIM 276
                 .|.:.|..||..|..|.:.....:||:  ....:....::.||              |..
Yeast   281 QSVIRYMDSSTSGTLSPPNIKRLSSNTERTSNTMSSSSAYLSALRGPAPNGALASNKKKRHRMEP 345

  Fly   277 LMIAASIRHCGGMTF----AYNADLYY-----------NTYFPDVDLG----WWLFGVTIGIGSV 322
            ..|.|.|..|..|.|    .:||.:||           |...|.:.:.    .:.|.....:.|:
Yeast   346 RTIRALIVGCMLMFFQQITGFNAFMYYAAIIFSKFNIKNPLLPPILIASTNFIFTFFAMYTMDSL 410

  Fly   323 GVVVGGIVSDKIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDPLWAMITLGLSYFFAEMWFGIV 387
            |             :..|..|..::....|:.....||....:.|...:.:.::.:.:.|  |.|
Yeast   411 G-------------RRAILLRTILIMTVGLLLCSVGFGHDQVNLLLISVVIYVAAYASAM--GSV 460

  Fly   388 FAIVVEIVPLRVRSSTIGVFLFVMNNIGGNLPILVDPVAKI--LGYRGSIMIFYAGFYGISSILF 450
            ....||.:||..||  .|.......|...|..:.:..::.|  :|...:::||  .|:.:.: .|
Yeast   461 PWTCVEFLPLNRRS--FGASCIACTNWLTNAFVSMTYLSTINTIGDENTMLIF--AFFTVCA-WF 520

  Fly   451 FITCFLLEGKP---DEVGQ 466
            |:..:..|.|.   :|||:
Yeast   521 FVYFWYPEVKGLSLEEVGR 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_001188550.1	MFS_1	94..416	CDD:284993	83/417 (20%)
CG14439	NP_001188550.1	MFS	107..452	CDD:119392	90/455 (20%)
CIN10	NP_010675.3	MFS_HMIT_like	45..528	CDD:340918	91/461 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910