DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14439 and slc17a5

DIOPT Version :9

Sequence 1:	NP_001188550.1	Gene:	CG14439 / 31614	FlyBaseID:	FBgn0029898	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	508	Identity:	104/508 - (20%)
Similarity:	194/508 - (38%)	Gaps:	116/508 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IPILEKLSGFYNTYVLAVLTIGYILGELGHYLIGVTSKQTAIELDYGDHACQQNTSMFNRHELP- 65
            :|:.  .|..||..::|:         ||.:::.......::.|          ..|.|....|
Frog    33 VPVC--CSARYNLALMAL---------LGFFMLYALRVNLSVAL----------VDMVNSTSTPR 76

  Fly    66 --TQCSAVMNETSCYALDFNGTGY-CEWNYNGLGIDYQILAGPTFILIFTIAGVFMGFAADKYNR 127
              |..:...:.||..|:..|.||. .:|:.|..|   .||.  :|...:.:..:..|:.|.|...
Frog    77 ENTTANICPDHTSAPAVLHNSTGQKYDWDANTQG---WILG--SFFYGYILTQIPGGYVAGKIGG 136

  Fly   128 VNMLTVCTVIFGIAMILQGTVKEYWQ--LVILRMIMAAGESGCNPLATGIMSDIFPEDKRALVMA 190
            ..:|....:...:..:|.....::..  |:.:|.:...||....|....:.:...|..:|:.:::
Frog   137 KQLLGFGILGTAVFTLLTPLAADFGAGCLIAVRALEGLGEGVTFPAMHAMWARWAPPLERSRLLS 201

  Fly   191 IFNWGIYGGYGIAFPVGRYITKLNFWNLGW-RVCYL--GAGVLTVIM-AALTGTTLREPE-RKAI 250
            :...|...|..::.||...|.    :.:.| .|.|:  ..|||..|| ..|...|   |: .::|
Frog   202 LSYAGAQLGTVVSLPVSGLIC----YYMDWIYVFYIFGTLGVLWFIMWCFLVSDT---PQSHRSI 259

  Fly   251 GEGDR---------QTSSGKPVSLWQVIKNPAMIMLMIAASIRHCGGMTFAYNADLY-----YNT 301
            .:.::         |.|..|.|....::|:..:..:::|    |     |:||...|     ..|
Frog   260 TDSEKEYILYTLQNQLSYRKSVPCCAMMKSLPLWAIIVA----H-----FSYNWTFYTLLTLLPT 315

  Fly   302 YFPDV---------------DLGWWLFGVTIGIGSVGVVVGGIVSDKIVAKMGIRSRAFVLAVSQ 351
            |..::               .||.|:|          :::.|:::|.:..|:.|.::    .|.:
Frog   316 YMKEILRFNAQENGFLSALPYLGCWVF----------MIMAGVIADCLREKLNISTK----VVRK 366

  Fly   352 LIATLPAFGSVYFDPLWAMITLGLSYFFAEMWFGIV-----FAIV------VEIVPLRVRSSTIG 405
            :..||...|...|  |.|....|.:|..|.::..:.     |::.      ::|.|     |..|
Frog   367 IFNTLGMLGPAIF--LLAAGYTGCNYSLAVVFLTLSTTLGGFSVAGYGINHLDIAP-----SFAG 424

  Fly   406 VFLFVMNNIGGNLPILVDPV-AKILGYRGSIMIFYAGFYGISSILFFITCFLL 457
            :.|.:.|.. ..:|.:|.|| ||.|.:..::..:...||..::|.||...|.:
Frog   425 LLLGITNTF-ATIPGMVGPVIAKALTHDNTVEQWQIVFYIAAAINFFGAIFFI 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_001188550.1	MFS_1	94..416	CDD:284993	71/368 (19%)
CG14439	NP_001188550.1	MFS	107..452	CDD:119392	79/392 (20%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	96/484 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010