Protein Alignment CG14439 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_572347.1
• Gene: CG14439 / 31614
• FlyBaseID: FBgn0029898
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 579
• Identity: 119/579 - (20%)
• Similarity: 203/579 - (35%)
• Gaps: 165/579 - (28%)

  Fly     6 EKLSGFYNTYVLAVLT-------IGYILGE--------LGHY--LIGVTSKQTAIELDYGDHACQ 53
            :|::|   |.|..|:|       .||.:|.        :.||  ::||       .||  |....
Human     4 DKVTG---TLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGV-------PLD--DRKAI 56

  Fly    54 QNTSMFNRHELPTQCSAVMNETSCYALDFNGTGYCE-------------WNYNGLGIDYQILAGP 105
            .|..:.:..|||         |..|:::...|.:.|             |:   |.:....:.|.
Human    57 NNYVINSTDELP---------TISYSMNPKPTPWAEEETVAAAQLITMLWS---LSVSSFAVGGM 109

  Fly   106 TFILIFTIAGVFMGFAADKYNRVNMLTVCTVIFGIAMILQGTVKEYWQLVILRMIMAAGE----- 165
            |       |..|.|:..|...|:..:.|..::..:..:|.|    :.:|....:::.||.
Human   110 T-------ASFFGGWLGDTLGRIKAMLVANILSLVGALLMG----FSKLGPSHILIIAGRSISGL 163

  Fly   166 -----SGCNPLATGIMSDIFPEDKRALVMAIFNWGIYGG------YGIAFPVGRYITKLNFWNLG 219
                 ||..|:..|   :|.|...|..:.......|..|      .|:.|.:|.|    :.|::
Human   164 YCGLISGLVPMYIG---EIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNY----DLWHI- 220

  Fly   220 WRVCYLG-AGVLTVIMAALTGTTLREPE----------------RKAIGEGD------------R 255
                .|| :||..::.:.|.......|.                ::..|..|            .
Human   221 ----LLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKERE 281

  Fly   256 QTSSGKPVSLWQVIKNPAMIMLMIAASIRHCGGMTFAYNADLYYNT-YFPDVDLGWWLFGVTIGI 319
            :.||.:.||:.|:..|.:....::.|.:.|........|...||:| .|....:...:: .|||:
Human   282 EASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVY-ATIGV 345

  Fly   320 GSVGVVVGGIVSDKIVAKMGIRSRAFVLAVSQLI--ATLPAFGSVYFDPL-W----AMITLGLSY 377
            |:|.:|... ||..:|.|.|.|| .|::.:|.:.  |...:.|.|..:.. |    :||.:.|..
Human   346 GAVNMVFTA-VSVFLVEKAGRRS-LFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFV 408

  Fly   378 FFAEM------WFGIVFAIVVEIVPLRVRSSTIGVFLFVMNNIGGNLPILVDPVAKILG-YRGSI 435
            .|.|:      ||     :|.|......|.:.:.:..|........:.:....:|...| |   :
Human   409 SFFEIGPGPIPWF-----MVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPY---V 465

  Fly   436 MIFYAGFYGISSILFFITCFLLEGKPDEVG----------QPESPKSH-PDAVLNARHM 483
            ...:||      :|...|.|.....|:..|          |.:|..:| |.|.:..:.:
Human   466 FFLFAG------VLLAFTLFTFFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_572347.1	MFS_spinster_like	67..457	CDD:340886	92/462 (20%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	109/538 (20%)