DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14439 and spns1

DIOPT Version :9

Sequence 1:	NP_001188550.1	Gene:	CG14439 / 31614	FlyBaseID:	FBgn0029898	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	XP_031748339.1	Gene:	spns1 / 100127684	XenbaseID:	XB-GENE-959720	Length:	526	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	103/471 - (21%)
Similarity:	187/471 - (39%)	Gaps:	100/471 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 DYQI------LAGPTFILIFTIAGVFMGFAADKYNRVNMLTVCTVIFGIAMILQGTV-KEY-WQL 154
            ||.|      |....||..:.......|:..|:|||..::.:....:.:..:|...| |:| |..
Frog    89 DYHISDSNSGLVQTVFICSYMFLAPVFGYLGDRYNRKLIMCIGISFWSLVTLLSSFVSKQYFWLF 153

  Fly   155 VILRMIMAAGESGCNPLATGIMSDIFPEDKRALVMAIFNWGIYGGYGIAFPVGRYITK-LNFWNL 218
            ::.|.::..||:..:.:|..|::|:|..|:|:.:::.|.:....|.|:.:..|..:|. ...|:.
Frog   154 LLTRGLVGVGEASYSTIAPTIIADLFLADQRSRMLSFFYFATPVGCGLGYIAGSKVTSTAGDWHW 218

  Fly   219 GWRVCYLGAGVLTVIMAALTGTTLREPERKAIGEGDRQTSSGKPV--SLW-----QVIKNPAMIM 276
            ..||. .|.|::.|::.....   :||.|.|:     :..|.:|:  :.|     .::|||:.|:
Frog   219 ALRVT-PGLGLVAVLLLIFVA---KEPPRGAL-----ERKSDRPLTNTSWFSDVKALLKNPSFIL 274

  Fly   277 --------LMIAASIRHCGGMTFAYNADLYYNT---------YFPDVDLGWWLFGVTIGIGSVGV 324
                    ..:..::...|......:..:.|.|         |...:..|    |:|...|.:||
Frog   275 STFGFTTVAFVTGALALWGPTYLMRSRRVIYKTEPCQGGICNYDDSMIFG----GITCVTGVLGV 335

  Fly   325 VVGGIVSDKIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDPLWAMITLGLSY---FFAEMWFGI 386
            :.|..:| |...|...|:...|.||. :|::.|   .:|....:|..:|..:|   |..|....:
Frog   336 LTGVEIS-KRYRKTNPRADPLVCAVG-MISSAP---FLYLSLAFADTSLVATYAFIFIGETLLSL 395

  Fly   387 VFAIVVEI---VPLRVRSSTIGVFLFVMNNIGGN------LPILVDPVAKILGYRGSIMI----- 437
            .:|:|.:|   |.:..|.||......|::::.|:      :.::.|.:.|  |...|.:|
Frog   396 NWALVADILLYVVIPTRRSTAEALQIVVSHLLGDAGSPYLIGVISDQIQK--GKAPSFLIQMRSL 458

  Fly   438 ----FYAGFYGISSILFFI-TCFLLEGKPDEVGQPESPKSHPDAVLNARHMHGHDNSVFSVDET- 496
                ....|.|:....||: |...:|            |....|.|       ....:...|||
Frog   459 EYALMICAFVGVIGGGFFLATALFIE------------KDRKRAEL-------FSQGLLPADETD 504

  Fly   497 -----LPSNGRPAQLP 507
                 :|..||..::|
Frog   505 AERIVVPKRGRSTKVP 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_001188550.1	MFS_1	94..416	CDD:284993	81/356 (23%)
CG14439	NP_001188550.1	MFS	107..452	CDD:119392	86/392 (22%)
spns1	XP_031748339.1	MFS_spinster_like	62..477	CDD:340886	90/407 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910