Protein Alignment CG3168 and DTR1

DIOPT Version :10

• Sequence 1: NP_572345.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_009739.1
• Gene: DTR1 / 852478
• SGDID: S000000384
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 668
• Identity: 143/668 - (21%)
• Similarity: 241/668 - (36%)
• Gaps: 144/668 - (21%)

  Fly     9 GKSEFYNVEAGLQPNYNQSAASNQASNHPTGQANAPATGNATSHIDNRAIIQPYSLGTGPKQPEY 73
            |...|.....|||.|..:|                 .|..:|.|                   ..
Yeast     2 GSEPFQKKNLGLQINSQES-----------------GTTRSTFH-------------------SL 30

  Fly    74 QFAADNRGYEPDSHANGKQQDVERDA----PDGGHGGHGPPGKGGKGGKGRKKSV---------- 124
            :...|:...|.....|.|:.:::.|.    ||..      |....:..|.:::.|
Yeast    31 EDLGDDVINESWDQVNQKRANIDHDVFHEHPDSS------PSLSAQKAKTKEEEVAVKSSNSQSR 89

  Fly   125 -PLPEPTAPI-VANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTE 187
             |.|:..|.| ...|.:...|..:|    |::.|..|...|..:.:.:    ||..:.:.|::..
Yeast    90 DPSPDTQAHIPYTYFSKDQRLIIFG----IIIFIGFLGPMSGNIYIPA----LPLLQREYDVSAT 146

  Fly   188 TKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIV-ISFMNAFCIVASSFSQTYSFFMLFRFLNG 251
            |.....|:......||..|||::||..|||.:.:| :|.|....|:.::.....:...:.|....
Yeast   147 TINATVSVFMAVFSVGPLFWGALADFGGRKFLYMVSLSLMLIVNILLAAVPVNIAALFVLRIFQA 211

  Fly   252 AALG-----GSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYF 311
            .|..     |:|.|     .:..|...||..:::.......|.:....:|.||:.:.
Yeast   212 FASSSVISLGAGTV-----TDVVPPKHRGKAIAYFMMGPNMGPIIAPIVAGLILMKG-------- 263

  Fly   312 TYNSWR-IFLLVCSLPSFLVGFLLF----YLPESPKFLLTRG------KKD----RALAIFRGIF 361
              |.|| :|    ...|.:.|..|.    .|||:.:.::..|      |||    .....|.|..
Yeast   264 --NYWRWLF----GFTSIMTGIALILVTALLPETLRCIVGNGDPKWGDKKDERENNESPFFEGNK 322

  Fly   362 VTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFT 426
            :::.:..||..:       .|.:.::...:..:.:.....:.....:.|.|.:..|.||..:.|:
Yeast   323 ISHRRLFPDIGI-------RKPVNNDAFFQENFPKPPKAGLTLYWKMIKCPPIIITSVSTALLFS 380

  Fly   427 FHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMES 491
               .||.    |...|:.:.|::..|.....|...|...|..|...||  |...||..:|.:::|
Yeast   381 ---SYYA----FSVTFSYYLEHDYRFTMLEIGAAYVCPGVAMLLGSQS--GGHLSDYLRSRWIKS 436

  Fly   492 LISLASALPAN---LLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFS-GAI 552
              ......||.   ||.::|:      ...|.||:..|..   ::|....|..||.||:.: |..
Yeast   437 --HPKKKFPAEFRLLLNLIGI------LLTICGTIGYGWA---IFFHYHFVVLLVFSALTAFGMT 490

  Fly   553 SAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLD----NYCPSPTFIVSGLL 613
            ..:|.::..| ||:||.:...| ||:|.....:|..|.:.:|.||.:    .:|.:...:.|.:.
Yeast   491 WCSNTSMTYL-TELFPKRAAGT-VAVSSFFRNVGAAISSAIILQLCNAMGIGWCFTGLGLCSSIS 553

  Fly   614 IGGGLMCLLLPNT-TRKE 630
            :.|.|..|:.... |.||
Yeast   554 LIGILYLLIFQRKYTAKE 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_572345.1	synapt_SV2	<137..626	CDD:130366	116/517 (22%)
DTR1	NP_009739.1	MFS_Tpo1_MDR_like	124..567	CDD:340881	110/494 (22%)