Protein Alignment CG3168 and TPO1

DIOPT Version :10

• Sequence 1: NP_572345.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_013072.1
• Gene: TPO1 / 850631
• SGDID: S000003951
• Length: 586
• Species: Saccharomyces cerevisiae
• Alignment Length: 678
• Identity: 132/678 - (19%)
• Similarity: 217/678 - (32%)
• Gaps: 242/678 - (35%)

  Fly    11 SEFYNVEAGLQPNYNQSAASNQASNHPTGQANAPATGNATSHIDNRAIIQPYSL-GTGPKQPEYQ 74
            |...|.|..|.|  :.|:.|:.:..|.||...  .||           ::|... |.|.|   |.
Yeast     5 SPISNKENHLLP--SDSSRSSSSDMHSTGTTG--TTG-----------VEPVDFTGEGAK---YT 51

  Fly    75 FAADNRG----------------------------------YEPDSHANGKQQDVERDAPDGGHG 105
            .|.:..|                                  .|||.    .:.|....||.||..
Yeast    52 TATEGNGGADLAIQRTTTMNSAAESEVNITRRLTKILTGSVNEPDR----VEVDYTNCAPMGGDR 112

  Fly   106 GHGPPGKGGKGGKGRKKSVPLP-------------EPTAPIVANFERAIELCGYGKFHYILLAIC 157
            .: ||.              ||             :|..|.....::.:.||.......|.:|:|
Yeast   113 PY-PPS--------------LPSRDLYEVTFDGPNDPLHPFNWPMKKKVLLCLVLCLDSIAIAMC 162

  Fly   158 GLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFI-GMMVGAYFWGSIADSFGRKKVLI 221
            ..:..|....:           |::....|....|...:|: |.......:..:::.:|||.||:
Yeast   163 SSIFASAVPQI-----------CEIYHVIEVVAILGITLFVLGFAASPVIYAPLSELYGRKGVLV 216

  Fly   222 VISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGP--VIWSYFAEFQPKAKRGSMLSFMAAF 284
            :.:|..|....|.:.::......:.||..|..  |:.|  |:.:.||:......||..:    |.
Yeast   217 LSAFGFALFQFAVATAENLQTIFICRFFGGFI--GAAPMAVVPAAFADMFDTNVRGKAI----AL 275

  Fly   285 WTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFY-LPESPKFLLTRG 348
            ::.| :||..:...::...|...|.:    .|..:::.|...:..|..:||: ....|..|:.:.
Yeast   276 FSLG-VFVGPILSPVMGSYIAQRTTW----RWLEYVVGCFASAVFVAIVLFFEETHHPTILVNKA 335

  Fly   349 KKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPI 413
            |:.|..:...||...:.          |:|:..|.:     |:...:|.|.       .||..|:
Yeast   336 KQMRKQSNNWGIHAAHE----------DVELSIKDI-----VQKTVTRPII-------MLFVEPL 378

  Fly   414 LRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGT 478
            |.|  |:|..:|.:.| .|.||..:|.:|  .|.|  .|                     :.||
Yeast   379 LLF--VTIYNSFVYGI-LYLLLEAYPLVF--VEGY--GF---------------------TENG- 414

  Fly   479 CSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLV 543
               ::|.                              ..||.|.|   :|:|.::::.:.
Yeast   415 ---ELPY------------------------------IALIIGMM---VCAAFIWYMDND----- 438

  Fly   544 VSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGII--GNIVIAQLL----DNYC 602
                                   :..:.||.|..:.  .|||..::  |.:....:|    ..|.
Yeast   439 -----------------------YLKRCRAKGKLVP--EARLYAMVIAGTVFPIGILWFCWTGYY 478

  Fly   603 PS------PTFIVSGLLIGGGLMCLLLP 624
            |.      ||  |.|..||.|||.:.||
Yeast   479 PHKIHWMVPT--VGGAFIGFGLMGIFLP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_572345.1	synapt_SV2	<137..626	CDD:130366	99/504 (20%)
TPO1	NP_013072.1	MFS_Tpo1_MDR_like	156..577	CDD:340881	97/490 (20%)