DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and Svop

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_081081.1	Gene:	Svop / 68666	MGIID:	1915916	Length:	548	Species:	Mus musculus

Alignment Length:	549	Identity:	137/549 - (24%)
Similarity:	243/549 - (44%)	Gaps:	76/549 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 RDAPDGGHGGHGPPGKGGKGGKGRKKSVPLPEPTA-------PIVANF--ERAIELCGYGKFHYI 152
            |...|...|.|....:|.:.|   .:::.|.:..|       |....|  |.|:|..|:|:|.:.
Mouse    24 RSEDDAASGEHDIQIEGVRVG---LEAIELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGRFQWK 85

  Fly   153 LLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRK 217
            |..:.||...::.|:::.:|.:.|...|:..|.:.....|.|::|||||..:..||:|:|.:|||
Mouse    86 LSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRK 150

  Fly   218 KVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMA 282
            ..|.:......:..:.|:|:..||:.::.|.|.|..:||. |...:.:|||.|...|...:..:.
Mouse   151 TGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGV-PQSVTLYAEFLPMKARAKCILLIE 214

  Fly   283 AFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTR 347
            .||..|.:|...||..::| ::|          ||..||:.:.|..|...|.|:||||.::.:..
Mouse   215 VFWAIGTVFEVLLAVFVMP-SLG----------WRWLLLLSAAPLLLFAVLCFWLPESARYDVLS 268

  Fly   348 GKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSP 412
            |.:::|:|..:.|...|....|...::...:      |..|.:::.:                :|
Mouse   269 GNQEKAIATLKRIATENGAPMPLGKLIISRQ------EDRGKMRDLF----------------TP 311

  Fly   413 ILRFTIVSI-TINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNN 476
            ..|:|.:.: .|.|:....||||::...|||            |:..||:::      :::::..
Mouse   312 HFRWTTLLLWFIWFSNAFSYYGLVLLTTELF------------QAGDVCSIS------SRKKAVE 358

  Fly   477 GTCS---SDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYF-VRS 537
            ..||   ..:.:..:|:.|.:..|..|..|:.:..:|.||||..:....:...:||.|::. :..
Mouse   359 AKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFIIFSLCSLLLFICIGR 423

  Fly   538 SVQNL---VVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLD 599
            :|..|   :..|..||...||..    ...||:||..||.|:......||:|.:|...:...:|:
Mouse   424 NVLTLLLFIARAFISGGFQAAYV----YTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLE 484

  Fly   600 NYCPSPTFIVSGLLIGGGLMCLLLPNTTR 628
            :.......:.||..:..|:....||..|:
Mouse   485 SSVYLTLAVYSGCCLLAGVASCFLPIETK 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	115/456 (25%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	117/476 (25%)
Svop	NP_081081.1	2A0119	9..519	CDD:273328	137/549 (25%)
Svop	NP_081081.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	521..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59613
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050