Protein Alignment CG3168 and SLC22A5

DIOPT Version :9

• Sequence 1: NP_001284957.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001295051.1
• Gene: SLC22A5 / 6584
• HGNCID: 10969
• Length: 581
• Species: Homo sapiens
• Alignment Length: 672
• Identity: 142/672 - (21%)
• Similarity: 236/672 - (35%)
• Gaps: 215/672 - (31%)

  Fly    13 FYNVEAGLQPNYNQSAASNQASNHPTGQANAPATGNATSHIDNRAIIQPYSLGTGPKQP----EY 73
            |:.:.|.:.||.....:|......|..:...|...|.:|...|..:  |..|..|.:.|    .|
Human    22 FFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAWRNHTV--PLRLRDGREVPHSCRRY 84

  Fly    74 QFAA----DNRGYEP-----------DSHANGKQ--QDV-------ERDAPDGGHGGHGPPGKGG 114
            :.|.    ...|.||           :|..:|.:  |||       |:|:  |.:...
Human    85 RLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTIVTEQDS--GAYNAM------- 140

  Fly   115 KGGKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAE 179
            |...|:|.::.||                                                  |:
Human   141 KNRMGKKPALCLP--------------------------------------------------AQ 155

  Fly   180 CDLDLNTETKGWLN-SIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFF 243
            .:|....:.|..|. |:.|:|:::|::..|.::|.||||.||.|...|.........||:.:..|
Human   156 WNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMF 220

  Fly   244 MLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIG--- 305
            ::...|.|                      .|.:.:::|||.....:...|:.  ||..|:|
Human   221 VVLFVLVG----------------------MGQISNYVAAFVLGTEILGKSVR--IIFSTLGVCI 261

  Fly   306 ------FTTPYFTY--NSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFR---- 358
                  ...|.|.|  ..||:.|:..::|..|...|.:::||||::|:::|:.:.|..|.|
Human   262 FYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAK 326

  Fly   359 --GIFVTNTKRRPDEYMVYDLEVDEKLLESNG--------NVKNKYSRMISGMVDHSRALFKSPI 413
              ||.|.:|...|.|..    ::..|..:|:.        |:     ||:
Human   327 ANGIVVPSTIFDPSELQ----DLSSKKQQSHNILDLLRTWNI-----RMV--------------- 367

  Fly   414 LRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGT 478
               ||:||.:..|..:||:||.:..|.|..
Human   368 ---TIMSIMLWMTISVGYFGLSLDTPNLHG----------------------------------- 394

  Fly   479 CSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLV 543
                   .:|:...:|....:||.:||.|.:..|.|::.:.......|.....|..|...:..|.
Human   395 -------DIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLA 452

  Fly   544 VSAIFSG--AISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIG-NIVIAQLLDNYCPSP 605
            ...:..|  .::||.:.:.....|::||.:|..||.:|..|:|||.|:. ..|.....|.:.|
Human   453 TVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLP-- 515

  Fly   606 TFIVSG-LLIGGGLMCLLLPNT 626
             :|:.| |.|...::.|.||.:
Human   516 -YILMGSLTILTAILTLFLPES 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	101/477 (21%)
		MFS	154..623	CDD:119392	108/498 (22%)
SLC22A5	NP_001295051.1	2A0119	12..544	CDD:273328	142/672 (21%)
		MFS	162..534	CDD:119392	106/467 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940