Protein Alignment CG3168 and SLC22A4

DIOPT Version :9

• Sequence 1: NP_001284957.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_003050.2
• Gene: SLC22A4 / 6583
• HGNCID: 10968
• Length: 551
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 105/474 - (22%)
• Similarity: 184/474 - (38%)
• Gaps: 113/474 - (23%)

  Fly   181 DLDLNTETKGW------------LNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVA 233
            |:.|:|....|            ..|:.|:|:::|::..|.::|.||||.||.           |
Human   122 DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLF-----------A 175

  Fly   234 SSFSQT-YSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAW 297
            :...|| :||..:|            .:.|..|.........|.:.:::.||.....:...|:.
Human   176 TMAVQTGFSFLQIF------------SISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVR- 227

  Fly   298 LIIPRTIGFTT---------PYFTY--NSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKD 351
             ||..|:|..|         |.|.|  ..||:.||..::|..|...|.:::||||::|:::.:..
Human   228 -IIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFR 291

  Fly   352 RALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKS-PILR 415
            .|..|.:.....|....|  .:::| .|:|         .|...:..:.::|    ||:: .|..
Human   292 EAEDIIQKAAKMNNIAVP--AVIFD-SVEE---------LNPLKQQKAFILD----LFRTRNIAI 340

  Fly   416 FTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCS 480
            .||:|:.:.....:||:.|.:..|.|                                      .
Human   341 MTIMSLLLWMLTSVGYFALSLDAPNL--------------------------------------H 367

  Fly   481 SDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVS 545
            .|...:.|:.:||.    :||.:.|.|.:..|.|::.:.|.....|.....:..|......|.:.
Human   368 GDAYLNCFLSALIE----IPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIG 428

  Fly   546 AIFSG--AISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFI 608
            .:..|  .|::|.:.|.....|::||.:|...|.::..|:|:|.||....:  .|..|.....:|
Human   429 LVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFV--YLGAYNRMLPYI 491

  Fly   609 VSG-LLIGGGLMCLLLPNT 626
            |.| |.:..|::.|..|.:
Human   492 VMGSLTVLIGILTLFFPES 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	96/443 (22%)
		MFS	154..623	CDD:119392	104/469 (22%)
SLC22A4	NP_003050.2	2A0119	12..518	CDD:273328	105/474 (22%)
		MFS	123..508	CDD:119392	103/469 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940