Protein Alignment CG3168 and Sv2b

DIOPT Version :9

• Sequence 1: NP_001284957.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001103223.1
• Gene: Sv2b / 64176
• MGIID: 1927338
• Length: 683
• Species: Mus musculus
• Alignment Length: 684
• Identity: 189/684 - (27%)
• Similarity: 303/684 - (44%)
• Gaps: 128/684 - (18%)

  Fly    72 EYQFAADNRGYEP-DSHANGKQQDVERDAPDGGHGGH---------------------------G 108
            :|::..:..||.| |.:....:|:.|.||......||                           .
Mouse     3 DYRYRDNYEGYAPSDGYYRSNEQNQEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKSKQTKMA 67

  Fly   109 PPGKGGKGGKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSF 173
            |....|.||:....:..: |....:...:|..|:.||:|:|.:.|..:.||...::.:::..:||
Mouse    68 PSRADGLGGQADLMAERM-EDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSF 131

  Fly   174 ILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQ 238
            .|||||.|:.|::..||.|..|:::|||.||:..|.:||..||||||.:...:||.....|||.|
Mouse   132 ALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQ 196

  Fly   239 TYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPR- 302
            .|..|:..|.::|..:|||.|::::||:||..:.|||..||::..||..|.::.:::||.|||.
Mouse   197 GYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHY 261

  Fly   303 TIGFT--TPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNT 365
            ..||:  |.|. ::|||:|::||:||:.:....|.::||||:|||..||.|.|..|.:.:..||.
Mouse   262 GWGFSMGTNYH-FHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNM 325

  Fly   366 KRRPDEYMVYDL-------EVDEKLLESNGNVKNKYSRMISGMV-------DHSRALFKSPILRF 416
            :.:.....|:.:       ::|| .:|...:....|.|.:...:       |::......|....
Mouse   326 RAKGTPEKVFTVSHIKTPKQMDE-FIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMN 389

  Fly   417 TIVSITINFTFHIGYYGLLMWFPELFNRF--EEYEK----------------------------- 450
            |::...:.||..:.||||.:|||::...|  |||:.
Mouse   390 TLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKL 454

  Fly   451 -------------AFPDQSAGVCAVTD------YVVNLAKEQSN-----------------NGT- 478
                         .|.|.....|...|      |..|...|.:.                 |.|
Mouse   455 VNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTF 519

  Fly   479 ------CSSDIPQS----VFMESLISLASALPANLLAILGMDMLGRKFFLIAGTM-TAGICSALM 532
                  |..|..:.    :::.|.:...|.||.|:::.|.||.:|| ..:|.|:| .:.:|...:
Mouse   520 LEQKEGCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGR-LKMIGGSMLISAVCCFFL 583

  Fly   533 YFVRSSVQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQL 597
            :|..|....:....:|.|...||..|||.:..|::||..|||...|.....:.|.|:||.:.|..
Mouse   584 FFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASF 648

  Fly   598 LDNYCPSPTFIVSGLLIGGGLMCLLLPNTTRKEL 631
            :......|..:.:..|:||||:.|.||.|..:.|
Mouse   649 VGITKVVPILLAAASLVGGGLIALRLPETREQVL 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	157/544 (29%)
		MFS	154..623	CDD:119392	162/564 (29%)
Sv2b	NP_001103223.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73		12/69 (17%)
		synapt_SV2	8..683	CDD:130366	188/679 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I3860
eggNOG	1	0.900	-	-		E33208_3B9V0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I2717
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59613
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	1	1.000	-	-		FOG0001322
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	1	0.900	-	-		OOG6_102121
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X658
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.770