Protein Alignment CG3168 and sv2a

DIOPT Version :9

• Sequence 1: NP_001284957.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 701
• Identity: 174/701 - (24%)
• Similarity: 292/701 - (41%)
• Gaps: 140/701 - (19%)

  Fly    32 QASNHPTGQANAPATGNATSHIDNRAIIQPYSLGTGPKQPEYQFAADNRGYEPDSHA-NGKQQDV 95
            ||.:....::|:.|..:..:|.|:                       ..|::.|... .|:.|.:
Zfish    61 QAQDGSYYRSNSRANDDEGAHSDS-----------------------TEGHDEDDEIYEGEYQGI 102

  Fly    96 ERDAPDGGHGGHGPPGKGGKG---------GKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHY 151
            .|:  |.........|..|:.         |:.||....|.:       .:|..::.||:|:|.:
Zfish   103 PRN--DSVEKADRQVGAVGQSQFRDMTQYEGERRKDQEELAQ-------QYETILQECGHGRFQW 158

  Fly   152 ILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGR 216
            .|..:.||...::.:::..:.|:|||||.|:.|:...||.|..|:::||||||:.||.:||..||
Zfish   159 TLYFVLGLALMADGVEIFVVGFVLPSAEKDMCLSEPNKGMLGLIVYLGMMVGAFVWGGLADRIGR 223

  Fly   217 KKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFM 281
            ::.|::...:|:.....|||.|.||.|:..|.|:|..:|||.|:::||::||..:.|||..||::
Zfish   224 RQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVFSYYSEFLAQEKRGEHLSWL 288

  Fly   282 AAFWTFGNLFVASLAWLIIPRTIGFTTPY---FTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKF 343
            ..||..|.::.|::||.|||. .|::...   :.::|||:|:|||:.||......|..:||||:|
Zfish   289 CMFWMIGGIYAAAMAWAIIPH-YGWSFQMGSAYQFHSWRVFVLVCAFPSVAAIAALTTMPESPRF 352

  Fly   344 LLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDL-------EVDEKLLESNGNV-------KNKY 394
            .|..||.|.|..|.:.:..||.:.:.....|:.:       ::|| |::..|..       :.|.
Zfish   353 YLENGKHDEAWMILKQVHDTNMRAKGYPERVFSVTTIKTVKQMDE-LVDMGGEATAWHQRWRIKL 416

  Fly   395 SRMISGMVDHSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPEL------------------ 441
            :.:...:..:...:|.....|.|.:.:.:.|:....||||.:|||::
Zfish   417 TNLFHQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYGLTVWFPDMIKYLQKQEYSSRTKVFIK 481

  Fly   442 -------FN--------RFEEY-----------EKAFPDQSAGVCAVTD---------------- 464
                   ||        |..||           ...|.|.....|...|
Zfish   482 EKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFEECYFEDITSSNTFFRNCTFIST 546

  Fly   465 --YVVNLAKEQ------------SNNGTCSSDIPQS-----VFMESLISLASALPANLLAILGMD 510
              |..:|.|.:            .|...|..|....     ::..|.:...:.||.|:::.|.||
Zfish   547 LFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNAYMIYFVSFLGTLAVLPGNIVSALLMD 611

  Fly   511 MLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATG 575
            .:||...|...::.:.:....:.|..|....:.:..:|.|...|:..|||.|..|::|:..|.|.
Zfish   612 KIGRLRMLAGSSVISCVSCFFLSFGNSESAMIALLCLFGGISIASWNALDVLTVELYPSDKRTTA 676

  Fly   576 VAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNT 626
            ........:|..::|..:....:......|....||.|..|..:.|.||.|
Zfish   677 FGFLNALCKLAAVLGISIFQSFVGITKAVPILFASGALAAGSFLALKLPET 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	143/544 (26%)
		MFS	154..623	CDD:119392	147/564 (26%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	174/701 (25%)
		MFS	162..725	CDD:119392	147/564 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	1	1.000	-	-		FOG0001322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102121
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X658
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850