DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and slc22a16

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001020659.1	Gene:	slc22a16 / 557279	ZFINID:	ZDB-GENE-041001-166	Length:	565	Species:	Danio rerio

Alignment Length:	522	Identity:	119/522 - (22%)
Similarity:	201/522 - (38%)	Gaps:	123/522 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 NFE------RAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNS 194
            ||:      :::|.||...:.:          :..|..:::          |.||..| :.||..
Zfish   109 NFQYEFFGNKSVESCGAFVYDH----------SEVEQSIVT----------DWDLVCE-REWLAK 152

  Fly   195 I----IFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALG 255
            :    ..:|:::||..:|..||..||:.||:..|.......|..:|:..|..|::.|||......
Zfish   153 LTQPTFMLGVLIGALMFGDAADRIGRRPVLMATSLCQFIFGVTVAFTGNYYLFVVMRFLLATVSS 217

  Fly   256 GSGPVIWSYFAEFQP-KAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIF 319
            |...|::.|..||.. |.:..:.:...||| ..|.:.||.:.:|:              ..|.|:
Zfish   218 GYLVVVFVYVTEFTGIKVRTWTSMHVHAAF-AVGIMVVALVGYLV--------------RVWWIY 267

  Fly   320 LLVCSLPSFLVGFLLF--YLPESPKFLLTRGKKDRA------LAIFRGIFVTNTKRRPDEYMVYD 376
            .::.:|.:  ..|||:  ..||:|.:|:.:|:...|      :|...|:        |....|.|
Zfish   268 QIILTLST--SPFLLYCWKFPETPFYLMAKGRYKEAQELLDTMAYINGL--------PPTLKVSD 322

  Fly   377 LE--VDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSIT---INFTFHIGYYGLLM 436
            |:  .|...|:.|........|:  .|:|    :|.|  |:....|.|   |.|...:|||
Zfish   323 LQDGCDRTPLKDNKQAMEVEKRL--SMLD----MFGS--LKMAGRSATCWAIWFIGSLGYY---- 375

  Fly   437 WFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALPA 501
                :|             |.|       .|||...|              ::...::.|..:|:
Zfish   376 ----VF-------------SLG-------SVNLGGNQ--------------YINLFLAGAVEVPS 402

  Fly   502 NLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSG--AISAANAALDCLIT 564
            .|:....||..|||.......:..|:...|:..|...|:.|.:....:|  ||:.|...:.....
Zfish   403 YLIGCFAMDRFGRKKTCAPALLLGGVACMLIIVVPQDVEVLAIVLSMTGKFAIAIAFGLIYLYTC 467

  Fly   565 EVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTTRK 629
            |::||.:|:..|....:..|:|.::....: .|.|.:...|..||..|....|::.:.||.|..:
Zfish   468 ELYPTIIRSLAVGSGSMMCRVGSVVAPFCV-YLADIWIYLPQLIVGILAFIIGILTMFLPETLGE 531

  Fly   630 EL 631
            .|
Zfish   532 PL 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	103/468 (22%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	110/488 (23%)
slc22a16	NP_001020659.1	2A0119	13..536	CDD:273328	119/522 (23%)
slc22a16	NP_001020659.1	MFS	158..526	CDD:119392	103/443 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940