DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	540	Identity:	129/540 - (23%)
Similarity:	209/540 - (38%)	Gaps:	136/540 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 KGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDL 182
            ||:.:|..:..|....:.:.|           ||      |:.:|:..:|  ...:..|.....|
Zfish    77 KGQYESCKMFTPVEMDIEDIE-----------HY------GINTTTSCID--GWVYKAPKDSSTL 122

  Fly   183 ----DLNTETKGW---LNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTY 240
                ||..|.|.:   ..||...|::|||..:|.:||.:||:...::..|:.....|..:||...
Zfish   123 ITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNI 187

  Fly   241 SFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIG 305
            ..::..||:.|..:.|.....:....|:...|||.........|:..|.:.::.:|:.|
Zfish   188 YVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIGLMLLSGVAYGI------ 246

  Fly   306 FTTPYFTYNSWRIFLLVCSLPSFLVG-FLLFY--LPESPKFLLTRGKKDRA-LAIFRGIFVTNTK 366
                    .:||:..||.|.|   || |.::|  ||||.::|||:||.|.| ..|.:...:...|
Zfish   247 --------RNWRVLQLVLSAP---VGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRK 300

  Fly   367 RRPDEYMVYDLEVDEKLL---ESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFH 428
                        |.|.||   |:....|:      |.|:|                      .|.
Zfish   301 ------------VSENLLDKMEAENTAKS------STMID----------------------LFR 325

  Fly   429 IGYY---GLL---MWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSV 487
            :||.   .|:   |||                    |.::..|.|:|     |.|....||
Zfish   326 VGYLRKRALIMCYMWF--------------------VTSLVYYGVSL-----NVGNFGLDI---- 361

  Fly   488 FMESLISLASALPANLLAILGMDMLGRKF-----FLIAGTMTAGICSALMYFVRSSVQNLVVSAI 547
            ::..||...:..||.|.....:...||:.     .|:.||... |..|:.  .:..:...|::.|
Zfish   362 YLTQLIFGMAEFPARLSCFPLIQRFGRRICQSVVLLLGGTACL-IIPAIP--AKYPIVVTVIAVI 423

  Fly   548 FSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPS-PTFIVSG 611
            ...:::|:.:.:.....|::||.:|..||.::.:.||:.||:..::  .|||.|..: |..|...
Zfish   424 GKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLI--GLLDVYHHAIPMIIYGS 486

  Fly   612 LLIGGGLMCLLLPNTTRKEL 631
            |...||.:..|||.|...:|
Zfish   487 LPFVGGALTFLLPETLNTDL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	110/473 (23%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	117/494 (24%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940