DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and Orct

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	124/508 - (24%)
Similarity:	200/508 - (39%)	Gaps:	88/508 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 ELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGW------------LNS 194
            |.|.|....|....:.|.:..|........|::...::.   ||:....|            .:|
  Fly    74 ERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKY---LNSAVTEWNLVCSRSLLSATSDS 135

  Fly   195 IIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGP 259
            :..:|:::|:..:|.::|..|||........:.....|.::.:..|..:.:.|.:.||...|...
  Fly   136 LFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFL 200

  Fly   260 VIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCS 324
            |.:....|....:.|......|..|::.|.:..|..|:.|              :.||...:..:
  Fly   201 VAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFI--------------HDWRWLQIAIT 251

  Fly   325 LPSFLVGFLLFY--LPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESN 387
            ||..|  ||.:|  :|||.::||.:|:||.|..|.......|....|:|  :|:..||| :.|..
  Fly   252 LPGLL--FLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNE--IYEQLVDE-VAEKK 311

  Fly   388 GNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFHIG-YYGLLMWFPELFNRFEEYEKA 451
            ...:...|:..:.:.|    |.:.|.||...:.|..::..:.| ||| |.|...
  Fly   312 KQDEMAASQPAATVFD----LLRYPNLRRKTLLIFFDWFVNSGVYYG-LSWNTN----------- 360

  Fly   452 FPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKF 516
                            ||...|..|           ||   ||.|..:|...|.:..::..||:.
  Fly   361 ----------------NLGGNQLVN-----------FM---ISGAVEIPGYTLLLFTLNRWGRRS 395

  Fly   517 FLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSG--AISAANAALDCLITEVFPTKLRATGVAIS 579
            .|....|.|||......||.|.:..|:|:....|  ||:::...:.....|.|||.:|..|:..|
  Fly   396 ILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGAS 460

  Fly   580 MVAARLGGIIGNIVIAQLL-DNYCPSPTFIVSGLLIGGGLMCLLLPNTTRKEL 631
            .:.||:|||:...:  :|| :.:.|.|..|...|.:..||:.||||.|..|.:
  Fly   461 SMVARVGGILAPYL--KLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPM 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	107/465 (23%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	115/486 (24%)
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	124/508 (24%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	105/422 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040