DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and Orct2

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	111/513 - (21%)
Similarity:	199/513 - (38%)	Gaps:	92/513 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 ELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGW------------LNS 194
            |.|.|....|....:.|.:..|........|::...::.   ||:....|            .:|
  Fly    74 ERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKY---LNSAVTEWNLVCGRDFMAATSDS 135

  Fly   195 IIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGP 259
            :..:|:::|:..:|.::|.:|||.:|.....:.....|.:..:..|..:...|.:.||...|...
  Fly   136 LFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFL 200

  Fly   260 VIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCS 324
            |.:....|.....||.....|:..|::.|.:..|..|             ||.:: ||...:..:
  Fly   201 VAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFA-------------YFVHD-WRWLQIALT 251

  Fly   325 LPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGN 389
            ||..:..|..:.:|||.::||.:|:||.|:|..:.....|.....||.:       .:||:...|
  Fly   252 LPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEAL-------SELLDEGEN 309

  Fly   390 VKNKYSRMISGM-VDHSRA-----LFKSPILRFTIVSITINFTFHIG-YYGLLMWFPELFNRFEE 447
            .:.|..:.:... :|....     ||..|.||...:.|.:::....| ||| |.|
  Fly   310 SEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYG-LSW---------- 363

  Fly   448 YEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDML 512
                                           .:|::..:|.:..:||.|..:||.:..:|.::..
  Fly   364 -------------------------------NTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRW 397

  Fly   513 GRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSG--AISAANAALDCLITEVFPTKLRATG 575
            ||:..|....:.||:.......:...:..|:|:....|  ||:|:...:.....|.|||.:|...
  Fly   398 GRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVA 462

  Fly   576 VAISMVAARLGGIIGNIV--IAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTTRKEL 631
            :..:.:.||:.|::...:  :|.:   :.|.|..|...|.:..||:.||||.|..|.:
  Fly   463 LGAASMVARISGMMAPFLNFLATI---WKPLPLLICGSLTLVAGLLSLLLPETHNKPM 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	96/471 (20%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	102/491 (21%)
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	111/513 (22%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	93/441 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040