DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and CG12783

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001262644.2	Gene:	CG12783 / 42019	FlyBaseID:	FBgn0038448	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	116/505 - (22%)
Similarity:	196/505 - (38%)	Gaps:	75/505 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 NFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGM 200
            :|:..:|..|:|:.|.......||:......:.:.|..|.|:|.|||.:|......|.:..|:|:
  Fly     3 HFDSVMEDIGFGRVHLFATVTLGLLQMLTIQETMGMGIIGPAAVCDLRMNEAQLASLTAAGFMGI 67

  Fly   201 MVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYF 265
            :..:||||.|.|..||:..|:....::..|.:||.|:.|::.|.:.||:....:.|...|..:|.
  Fly    68 ICSSYFWGYITDKKGRRWTLLRTITISNLCSLASMFTVTFTGFFVMRFITCIFVAGPSFVAATYL 132

  Fly   266 AEFQPKAKRGSMLSFMAAFWTF-GNLFVASLAWLIIPRTIGF------TTPYFTYNSWRIFLLVC 323
            :||   .....|:..:...:.| |...::..||..:..:.|.      .....|...||:...:.
  Fly   133 SEF---CSHRIMVRSITHLYMFTGFAMISCPAWATLFLSSGLIEFEEKLVGSLTLRPWRVLGCLY 194

  Fly   324 SLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDE-----YMVYDLEVDEKL 383
            .||..:...||..|||||||||..|:..|.|.....|...||.|...|     .:.|...|..|.
  Fly   195 ILPGVVAFLLLLLLPESPKFLLMIGETKRGLDTMEWISRKNTGRTLSEDQMKRLLAYQEHVQVKR 259

  Fly   384 LESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEY 448
                   :.::......|:|.:..|.:.|...:......:.|...:..:||.:|:..:.||
  Fly   260 -------RKEHQNFFRSMLDDAMPLVRKPYGGYFTCVCMVMFVLGLLTHGLGIWYTAMRNR---- 313

  Fly   449 EKAFPDQSAGVCAVTDYVVNLAKEQSNNGT-CS-SDIPQS-VFMESLISLASALPANLLAILGMD 510
                       |       |:.:..:|..| |. ..:|:: .|:|:...|......:........
  Fly   314 -----------C-------NMRQGNTNGMTFCQVLFVPETGPFIETESDLDVVCSDSFKGFNDSF 360

  Fly   511 MLGRKFFLIAGTMTAGICSALMYFVRSSVQ---NLVVSAIFSGAISAANAALDCLITEVF----- 567
            :||..:.::     ..|..|.::.|...|.   :||.|:.|...:..|...:..|.:.||
  Fly   361 VLGFVYVVL-----YNISWASLFCVHKKVMFVFSLVASSTFGFLLIFATNHMLQLFSLVFLIAFP 420

  Fly   568 ---------------PTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYC 602
                           ||.||...:.||::..|.|...|.:::...:...|
  Fly   421 GIIIGLLGGSLLVFVPTYLRGKALCISLMWCRCGAAFGAMLVGSKIQYNC 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	111/486 (23%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	111/487 (23%)
CG12783	NP_001262644.2	synapt_SV2	<2..>310	CDD:130366	81/316 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3556
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.070