DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and CG14691

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	147/525 - (28%)
Similarity:	261/525 - (49%)	Gaps:	42/525 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 ANFERAIELCGYGKFHYILLAICGLVS--TSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIF 197
            |:||.||..||:|.|:..:|  |..|.  |:......::|:::|||||||||:...||.|:::.:
  Fly    13 ADFETAIAECGFGLFNVFIL--CSAVPCLTAMVFSASALSYVMPSAECDLDLSIVDKGMLHAVTY 75

  Fly   198 IGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIW 262
            .||::.|..||.|||:.||:.|||...:::.|.::.:|.||..:..|.|:|.:|..:.|...|:.
  Fly    76 AGMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVV 140

  Fly   263 SYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPS 327
            ||.|||..|..|..::.|:....:.|::.:..|::|::|..|.||.....:.:|::||.|.|.||
  Fly   141 SYLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPS 205

  Fly   328 FLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDL------EVDEKLLES 386
            .|.|||..:||||||||:::|...:||...:.|:..|.::..:.|.:..|      ..|:  |:.
  Fly   206 LLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDD--LDG 268

  Fly   387 NG---NVKNKYSRMISGMVD---HSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRF 445
            .|   .::.::||..|..:|   ..:.:|.||.|..::....::|...:....:.:|.|::|...
  Fly   269 TGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFATM 333

  Fly   446 EEYEKAFPDQSAGVCAVTDYVVNLAK---EQSNNGTCSSDIPQSVFMES-------LISLASALP 500
            ...:....:.:: :|||.::..| ||   |:.....|:.......::.:       |:......|
  Fly   334 NAMDTLGANDTS-MCAVLEHNAN-AKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFP 396

  Fly   501 ANLLAILGMDMLGRKFFLIAGTMTAGICSAL---MYFVRSSVQNLVVSAIFSGAISAANAALDCL 562
            .....::...:|  |.||.       ||..|   :|||::|:..::|||::...:......:..:
  Fly   397 LMRFQVVSNHIL--KVFLF-------ICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGM 452

  Fly   563 ITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTT 627
            ...:|||.:|...:.:.|...|||.:.||:::...:...|.:|...:..|:....|..|.|....
  Fly   453 SVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSCLAPFLWLCSLMSIAFLFSLFLKVDD 517

  Fly   628 RKELN 632
            .:.||
  Fly   518 EQSLN 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	131/475 (28%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	135/495 (27%)
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	66/187 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	1	0.950	-	0	Normalized mean entropy	S5294
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.020