DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and slc22a4

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_989323.1	Gene:	slc22a4 / 394948	XenbaseID:	XB-GENE-5858686	Length:	553	Species:	Xenopus tropicalis

Alignment Length:	469	Identity:	111/469 - (23%)
Similarity:	198/469 - (42%)	Gaps:	98/469 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 ECDLDLNTETKGWL-NSIIFIGMMVGAYFWGSIADSFGRKKVLIV-ISFMNAFCIVASSFSQTYS 241
            |.|:....:.||.| .|:.|:|:::|::..|.::|||||||:|.| ::....|.|| ..||.::.
Frog   127 EWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIV-QVFSTSWE 190

  Fly   242 FFMLFRFLNGAALGGSGPVIWSYFAEF----QPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPR 302
            .|.:. ||    :.|.|. |.:|.|.|    :...|...::     |.|.|.....::.::::
Frog   191 MFAIL-FL----IVGMGQ-ISNYVAAFILGTEILGKSARII-----FSTLGTCIFFAIGYMML-- 242

  Fly   303 TIGFTTPYFTY--NSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNT 365
                  |.|.|  ..||..||..::|......|.:.:||||::|:.:|:.:.|..|.|.....|
Frog   243 ------PLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPQWLICKGRLEEAEVIIRKAAKIN- 300

  Fly   366 KRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILR-FTIVSITINFTFHI 429
             |.|...:::.....|.:.|..   |..|:     ::|    |.|:..:| .||:::.:.....|
Frog   301 -RVPAPAVIFKTTELEDIAERQ---KRSYT-----LLD----LVKTFNVRIITIMTVFLWLITSI 352

  Fly   430 GYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLIS 494
            ||:|:.:..|.|..                                          ..|:...:.
Frog   353 GYFGISLNTPNLHG------------------------------------------DPFLNCFLL 375

  Fly   495 LASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSG--AISAANA 557
            .|..:|:|:.|.|.:..:.|::.:....:..|:...|:..|...:|.|....:..|  .::||.:
Frog   376 AAIEVPSNIFAWLLLRYISRRYSMCGSLLLGGVVLLLIQLVPLDLQILSTVLVMVGKFGVTAAFS 440

  Fly   558 ALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVI-----AQLLDNYCPSPTFIVSGLLIGGG 617
            .:.....|::||.:|.|||.|..|::|:|.:|....:     .:||      |..::..|.:..|
Frog   441 MVYVYTAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYNRLL------PYILMGSLTVANG 499

  Fly   618 LMCLLLPNTTRKEL 631
            ::.|..|.|..|.|
Frog   500 ILVLFFPETFGKPL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	101/434 (23%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	107/459 (23%)
slc22a4	NP_989323.1	2A0119	12..516	CDD:273328	111/469 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000