DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and slc22a7b.1

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_021322800.1	Gene:	slc22a7b.1 / 393320	ZFINID:	ZDB-GENE-040426-1311	Length:	560	Species:	Danio rerio

Alignment Length:	551	Identity:	124/551 - (22%)
Similarity:	209/551 - (37%)	Gaps:	128/551 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GKGGKGRKK----SVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFI 174
            |.|...:|:    |||..|...|      .:..:..:.:|..::.:              |.|..
Zfish    68 GLGNLTQKERLIVSVPAQEDGTP------ASCHMFAHPQFQLLINS--------------SSSSA 112

  Fly   175 LPSAEC-----------------DLDLNTETKGWLN---SIIFIGMMVGAYFWGSIADSFGRKKV 219
            ||..||                 ..||..:.:|...   :|.|:|:|.||.|:|.:.|.:||:.:
Zfish   113 LPVVECQNGWHFDNSTFISTLATQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSM 177

  Fly   220 LIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAF 284
            |:|....:....|.|:||.:|..|..||||.|.||.|...:......|:.....|..|..|.:..
Zfish   178 LLVSYVFSIVFSVTSAFSSSYIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMS 242

  Fly   285 WTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGK 349
            |:.||:.:|..|:::              ..||:.:::.:.|.||.....:::|:|.::|:..||
Zfish   243 WSIGNMLLAGFAFMV--------------TDWRLLIVIVTAPLFLATATWWWIPDSARWLIANGK 293

  Fly   350 KDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVK-NKYSRMISGMVDHS------RA 407
            .:.|..........|.:                 |:....|| ...|.:::  |||.      ..
Zfish   294 TETAYKYLHKCATFNQR-----------------LDFTSRVKPETLSTVVT--VDHRGHSYTYLD 339

  Fly   408 LFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKE 472
            |.|:|.||        ..|...|    ::|:                   || |.|.|.::|
Zfish   340 LVKTPQLR--------KLTLFTG----IVWY-------------------GV-ASTYYGISL--- 369

  Fly   473 QSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRS 537
               |.|.....|   ::...|..|..:||.:|....::.:||:.......:..|.|..:.....:
Zfish   370 ---NITGFGLDP---YLTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPT 428

  Fly   538 SVQNL--VVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDN 600
            .....  |::.:..|...|:...:....||::||.:|..|:..:...||:|..|..:::. |.|.
Zfish   429 EYWTFRTVIAVLGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIML-LEDI 492

  Fly   601 YCPSPTFIVSGLLIGGGLMCLLLPNTTRKEL 631
            :...|..|...:.|..|::.||||.|....|
Zfish   493 WKLLPEVIFCSMAIFCGIIALLLPETNNASL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	104/477 (22%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	110/497 (22%)
slc22a7b.1	XP_021322800.1	Sugar_tr	22..526	CDD:331684	124/551 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940