DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_941052.1	Gene:	Slc22a20 / 381203	MGIID:	2685809	Length:	556	Species:	Mus musculus

Alignment Length:	465	Identity:	120/465 - (25%)
Similarity:	206/465 - (44%)	Gaps:	90/465 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 ILPSA---ECDLDLNTET-KGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVAS 234
            |.||.   |.||.....| :....||...|::|||..:|.:||..|||..|:......|....|:
Mouse   117 IFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAAT 181

  Fly   235 SFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKR---GSMLSFMAAFWTFGNLFVASLA 296
            ::..::|.:.:||||.|....|......|...|:.|...|   |.:|.|.   :|.|.|.:|.:|
Mouse   182 AYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFS---FTLGQLILAGVA 243

  Fly   297 WLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLL-FYLPESPKFLLTRGKKDRALAIFRGI 360
            :||.|              ||......|.| |||.||. ::||||.::||..||..:|:...:.:
Mouse   244 YLIRP--------------WRWLQFAVSAP-FLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKV 293

  Fly   361 FVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSP-ILRFTIVSITIN 424
            .:.|.::...|.:..:: |...:.:...:|:...|     ::|    ||::| |.|.|...:.:.
Mouse   294 AMMNGRKAEGERLTTEV-VSSYIQDEFASVRTSNS-----ILD----LFRTPAIRRVTCCLMGVW 348

  Fly   425 FTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFM 489
            |:..:.||||.|          :.:|         ..::.|:|                 |::|
Mouse   349 FSNSVAYYGLAM----------DLQK---------FGLSIYLV-----------------QALF- 376

  Fly   490 ESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNL--VVSAIFSGAI 552
             .:|.    :||.|:|...|..:||:..:.:..:.||:......|:...:|.|  |.:|:..|.:
Mouse   377 -GIID----IPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCL 436

  Fly   553 SAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIV-----IAQLLDNYCPSPTFIVSGL 612
            :::...:.....|::||::|..|:..:.|.|||||::..::     |:.:|    |..:|..:.:
Mouse   437 ASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVL----PPVSFGATSV 497

  Fly   613 LIGGGLMCLL 622
            |.|..:.|.|
Mouse   498 LAGMAVACFL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	113/439 (26%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	120/465 (26%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	120/465 (26%)
		MFS	138..507	CDD:119392	112/442 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..556
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940