DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and CG31272

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	574	Identity:	168/574 - (29%)
Similarity:	271/574 - (47%)	Gaps:	52/574 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 NRGYEPDSHANGKQQD-VERDAPDGGHGGHGPPGKGGKGGKGRKKSVPLPEPTAPIVANFERAIE 142
            ::|.|.|..|:|.... .|.:|                            .||....|.|::|||
  Fly    14 SKGLENDKDADGNSDSTAEAEA----------------------------TPTEEGSATFDKAIE 50

  Fly   143 LCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFW 207
            ..|:|.|:.:||.:.....::...:..|||:|||.|||||.|..|.||.||::.:.||.:.|..|
  Fly    51 GAGFGIFNLMLLIVSIPAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAW 115

  Fly   208 GSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKA 272
            |.:||:.||||:|.....::|.|:..|:.||.:|..::|:||.|..:.|...|:::|..|.....
  Fly   116 GYLADTKGRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPK 180

  Fly   273 KRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYL 337
            .|.|:|..:....:...:.:..|||.|.||...|.......:||:|||.|..:||.:.|.:...:
  Fly   181 HRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSM 245

  Fly   338 PESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDL------------EVDEKLLESNGNV 390
            ||||:||:.:|:.:.||..|:.|:..||::..|.|.:..|            ||...:.|.:|.|
  Fly   246 PESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEV 310

  Fly   391 KNK-YSRMIS----GMVDHSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYE- 449
            ..| .||.::    ..:...:.|.:.|:|...|....:.|...:|...:.:|.|:||....|||
  Fly   311 PTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEA 375

  Fly   450 -KAFPDQSAGVCAVTDYVVNLAKEQSNN--GTCSSD--IPQSVFMESLISLASALPANLLAILGM 509
             .|.......:|.:.::.||...|.:.|  ..||..  |...:::.::|..|:.......|...:
  Fly   376 LHAGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGIL 440

  Fly   510 DMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSGAISAANAALDCLITEVFPTKLRAT 574
            ..||.|..:..|...:|....::||..||:..|:|||.|......|.::|...:..:|||:||..
  Fly   441 RALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTV 505

  Fly   575 GVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTTR 628
            .|||:|:..|.|.:.||::....:...|..|..:||.:||..|::.:.||:..:
  Fly   506 VVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLILSGILSISLPDPAK 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	143/471 (30%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	148/491 (30%)
CG31272	NP_650013.3	MFS	62..555	CDD:119392	148/492 (30%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	140/449 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	1	0.950	-	0	Normalized mean entropy	S5294
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.020